STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A139W8V5Histone domain-containing protein. (625 aa)    
Predicted Functional Partners:
D7GXP9_TRICA
Histone H2B; Belongs to the histone H2B family.
 
 
 0.925
D6W951_TRICA
Histone H2A; Belongs to the histone H2A family.
 
 
 0.863
D7EKP1_TRICA
Histone H2B; Belongs to the histone H2B family.
 
 
 0.861
A0A139W9I4
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
 
 
 0.844
A0A139WGM2
JmjC domain-containing histone demethylation protein 1-like protein.
    
 0.839
D2A453_TRICA
Uncharacterized protein.
    
 0.833
D6WUS4_TRICA
Putative histone-binding protein Caf1-like Protein.
   
 0.828
D6WL79_TRICA
Uncharacterized protein.
    
 0.824
D6WKQ6_TRICA
Uncharacterized protein.
   
 0.819
D6WGH2_TRICA
Retinoblastoma-binding protein 5 homolog-like Protein.
    
 0.815
Your Current Organism:
Tribolium castaneum
NCBI taxonomy Id: 7070
Other names: T. castaneum, red flour beetle, rust-red flour beetle
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.