Proteins whose genes are observed to be correlated in expression, across a large number of experiments.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
Node Content
empty nodes: proteins of unknown 3D structure
filled nodes: a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A139WCT6
Carboxypeptidase A. (490 aa)
Predicted Functional Partners:
D6X251_TRICA
Cyclin-G-associated kinase-like Protein.
0.930
D6WVM9_TRICA
Carboxyopeptidase A.
0.412
D2A3Y3_TRICA
Carboxypeptidase A.
0.400
Your Current Organism:
Tribolium castaneum
NCBI taxonomy Id: 7070 Other names: T. castaneum, red flour beetle, rust-red flour beetle