STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A139WEN5AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa)    
Predicted Functional Partners:
D6W7L4_TRICA
AP-2 complex subunit alpha; Adaptins are components of the adapter complexes which link clathrin to receptors in coated vesicles.
   
 0.999
Ap2m1
AP-2 complex subunit mu-like Protein; Belongs to the adaptor complexes medium subunit family.
   
 0.999
D2A641_TRICA
AP-2 complex subunit beta-like Protein.
    
 0.997
A0A139WLF8
Intersectin-2-like Protein.
   
 0.996
A0A139WP06
FCH domain only protein 2-like Protein.
    
 0.942
D6WTU9_TRICA
Epidermal growth factor receptor substrate 15-like 1.
    
 0.937
Chc
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.
    
 0.929
D6X1U8_TRICA
AP-1 complex subunit gamma.
    
 0.922
D6X1A3_TRICA
NECAP-like protein CG9132.
    
  0.911
A0A139WGC0
AP-3 complex subunit delta; Belongs to the adaptor complexes large subunit family.
    
 0.910
Your Current Organism:
Tribolium castaneum
NCBI taxonomy Id: 7070
Other names: T. castaneum, red flour beetle, rust-red flour beetle
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.