STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A139WER6Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (89 aa)    
Predicted Functional Partners:
D6X1W3_TRICA
F-box domain-containing protein.
   
 0.866
Skp1
S-phase kinase-associated protein 1; Belongs to the SKP1 family.
    
 0.771
D2A0W3_TRICA
G2/mitotic-specific cyclin-A-like Protein; Belongs to the cyclin family.
   
 0.749
D6WX89_TRICA
G2/mitotic-specific cyclin-A-like Protein; Belongs to the cyclin family.
   
 0.749
D2A4I9_TRICA
Cyclin-dependent kinase 1-like Protein; Belongs to the protein kinase superfamily.
   
 0.704
D2A537_TRICA
Cdc2 kinase-like protein.
   
 0.688
D6WTL2_TRICA
Cyclin-dependent kinase 1-like Protein; Belongs to the protein kinase superfamily.
   
 0.688
Cdc2
Cdc2 kinase-like protein.
   
 0.688
D1ZZI2_TRICA
Uncharacterized protein.
   
 0.675
D6WH94_TRICA
CYCLIN domain-containing protein; Belongs to the cyclin family.
   
 0.675
Your Current Organism:
Tribolium castaneum
NCBI taxonomy Id: 7070
Other names: T. castaneum, red flour beetle, rust-red flour beetle
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.