STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A139WI52SAGA-associated factor 11; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. (255 aa)    
Predicted Functional Partners:
e(y)2
Enhancer of yellow 2 transcription factor; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex [...]
   
 0.951
D6WR38_TRICA
SAGA-associated factor 29 homolog-like Protein.
    
 0.950
A0A139WFG5
Transcriptional adapter.
    
 0.932
D6WAL9_TRICA
Transcriptional adapter 1-like Protein.
    
 0.912
D6WJN2_TRICA
Histone acetyltransferase KAT2A-like Protein.
    
 0.900
D6WYJ1_TRICA
Ubiquitin carboxyl-terminal hydrolase.
    
 
 0.898
D6W6N3_TRICA
SCA7 domain-containing protein.
    
 
 0.884
D6WIZ3_TRICA
Transcriptional adapter 2A-like Protein.
    
 0.874
D6WJV3_TRICA
Transcription initiation factor TFIID subunit 10-like Protein.
    
 0.863
D2A4J4_TRICA
Transcriptional adapter 3-like Protein.
    
 0.856
Your Current Organism:
Tribolium castaneum
NCBI taxonomy Id: 7070
Other names: T. castaneum, red flour beetle, rust-red flour beetle
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.