STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A139WIA93-hydroxy-3-methylglutaryl coenzyme A reductase. (863 aa)    
Predicted Functional Partners:
D6WTE1_TRICA
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
  
 
 0.999
D2A4R0_TRICA
Mevalonate kinase.
  
 0.995
D6WSF8_TRICA
3-hydroxy-3-methylglutaryl coenzyme A reductase.
  
  
 
0.901
D6W7Q3_TRICA
3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic-like Protein.
    
 0.835
D6WE42_TRICA
Diphosphomevalonate decarboxylase.
  
  
 0.807
Fpps
Farnesyl pyrophosphate synthase.
  
 
 0.763
D6WWC8_TRICA
UbiA prenyltransferase domain-containing protein 1 homolog-like Protein.
   
 
 0.753
A0A139WMR2
Zinc finger protein 221-like Protein.
      
 0.732
D2A3I9_TRICA
Fatty acid hydroxylase domain-containing protein 2-like Protein; Belongs to the sterol desaturase family.
   
  
 0.724
D6WP58_TRICA
Isopentenyl-diphosphate Delta-isomerase 1-like Protein.
 
  
 0.672
Your Current Organism:
Tribolium castaneum
NCBI taxonomy Id: 7070
Other names: T. castaneum, red flour beetle, rust-red flour beetle
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.