STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A139WIL11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1205 aa)    
Predicted Functional Partners:
A0A139WM82
Phosphoinositide phospholipase C.
   
 
0.951
A0A139WJG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
  
 
0.950
D6WLT9_TRICA
Guanine nucleotide-binding protein subunit beta-2-like Protein.
     
 0.934
D6WZL6_TRICA
Kinase; Belongs to the inositol phosphokinase (IPK) family.
     
 0.932
A0A139WEE0
Uncharacterized protein.
   
  0.925
A0A139WML5
G protein alpha q subunit-like Protein.
    
 0.925
A0A139WIT2
Uncharacterized protein.
     
 0.924
D2A609_TRICA
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha-like Protein.
     
 0.919
D6X3B1_TRICA
Type I inositol 1,4,5-trisphosphate 5-phosphatase-like Protein.
   
 
 0.917
A0A139WLV0
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
     
 0.916
Your Current Organism:
Tribolium castaneum
NCBI taxonomy Id: 7070
Other names: T. castaneum, red flour beetle, rust-red flour beetle
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.