STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A139WNC4Serine/threonine-protein kinase Nek8-like Protein. (715 aa)    
Predicted Functional Partners:
A0A139WD62
Extracellular serine/threonine protein kinase FAM20C-like Protein.
     
 0.596
D6W9Q2_TRICA
Serine/threonine-protein kinase PLK4-like Protein.
  
0.585
Polo
Polo.
  
0.580
twe
Twine.
   
  
 0.546
D2A537_TRICA
Cdc2 kinase-like protein.
  
 
 
0.465
PAN3
PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...]
      
 0.446
Cdc2
Cdc2 kinase-like protein.
  
 
 
0.437
D2A4I9_TRICA
Cyclin-dependent kinase 1-like Protein; Belongs to the protein kinase superfamily.
  
 
 
0.431
D6WWD3_TRICA
Uncharacterized protein.
      
 0.431
D6WTL2_TRICA
Cyclin-dependent kinase 1-like Protein; Belongs to the protein kinase superfamily.
  
 
 
0.428
Your Current Organism:
Tribolium castaneum
NCBI taxonomy Id: 7070
Other names: T. castaneum, red flour beetle, rust-red flour beetle
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.