STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A139WPC3Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (359 aa)    
Predicted Functional Partners:
D6WC45_TRICA
Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.
   
 0.999
D2A430_TRICA
Segment polarity protein dishevelled-like Protein.
    
 0.966
D6W785_TRICA
FUN14 domain-containing protein 1-like Protein.
   
 
 0.964
D6WD77_TRICA
FUN14 domain-containing protein 1B-like Protein.
     
 0.945
D6X1B7_TRICA
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
    
 0.941
D6WL41_TRICA
FACT complex subunit spt16-like Protein.
   
 0.937
D6WGD6_TRICA
Ribosomal RNA-processing protein 7 homolog A-like Protein.
   
 0.934
D6WRZ2_TRICA
Nucleolar protein 6.
    
 0.926
A0A139WA38
PIN2/TERF1-interacting telomerase inhibitor 1-like Protein.
    
 
 0.824
D1ZZY9_TRICA
ESF1 homolog-like Protein.
   
   0.824
Your Current Organism:
Tribolium castaneum
NCBI taxonomy Id: 7070
Other names: T. castaneum, red flour beetle, rust-red flour beetle
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.