STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
D2A1C8_TRICAGlutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily. (112 aa)    
Predicted Functional Partners:
D6WCU7_TRICA
Anamorsin homolog; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex. Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase. Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RN [...]
    
 
 0.904
A0A139WEV1
Iron-sulfur cluster assembly 2 homolog, mitochondrial-like Protein.
  
 0.811
D6X3X6_TRICA
Iron-sulfur cluster assembly 1 homolog, mitochondrial-like Protein.
  
 0.798
D2A5B5_TRICA
GPN-loop GTPase 3; Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family.
   
    0.744
D6WAB3_TRICA
39S ribosomal protein L2, mitochondrial-like Protein.
   
    0.744
D6WDC6_TRICA
Actin-related protein 2/3 complex subunit 1A-like Protein.
   
    0.744
D6WGV2_TRICA
39S ribosomal protein L38, mitochondrial-like Protein.
   
    0.744
D6WIS5_TRICA
Putative prefoldin subunit 6-like Protein.
   
    0.744
D6WRZ2_TRICA
Nucleolar protein 6.
   
    0.744
D6WX24_TRICA
Zinc finger CCHC domain-containing protein 4-like Protein.
   
    0.744
Your Current Organism:
Tribolium castaneum
NCBI taxonomy Id: 7070
Other names: T. castaneum, red flour beetle, rust-red flour beetle
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.