STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
D2A3V8_TRICAHistone-lysine N-methyltransferase pr-set7-like Protein. (288 aa)    
Predicted Functional Partners:
A0A139W9I4
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.789
A0A139W9W1
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.789
D2A3W3_TRICA
Phosphatidylinositol 4-kinase alpha-like Protein; Belongs to the PI3/PI4-kinase family.
 
      0.759
D6WQQ2_TRICA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
   0.745
D6WGH2_TRICA
Retinoblastoma-binding protein 5 homolog-like Protein.
    
 0.699
D2A161_TRICA
Histone-lysine N-methyltransferase Suv4-20-like Protein.
      
 0.682
D6WLT6_TRICA
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3-like Protein.
    
  0.663
D7EJV5_TRICA
P53 domain-containing protein.
   
 0.574
D7EJV6_TRICA
Tumor protein p73-like Protein.
   
 0.574
D1ZZL7_TRICA
Protein dpy-30 homolog-like Protein.
    
 
 0.570
Your Current Organism:
Tribolium castaneum
NCBI taxonomy Id: 7070
Other names: T. castaneum, red flour beetle, rust-red flour beetle
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.