STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
D6W702_TRICAFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. (350 aa)    
Predicted Functional Partners:
D6W9X5_TRICA
Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
  
 
 0.997
D6X3T3_TRICA
Frataxin homolog, mitochondrial-like Protein.
    
 0.968
A0A139WBV5
Protoheme IX farnesyltransferase, mitochondrial-like Protein.
   
 
 0.951
A0A139WPD2
Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family.
 
  
 0.944
D6X0A1_TRICA
Cytochrome c heme lyase; Links covalently the heme group to the apoprotein of cytochrome c.
     
 0.912
D6WJU3_TRICA
Porphobilinogen deaminase-like Protein.
  
  
 0.704
D2A1Q2_TRICA
HemK methyltransferase family member 1-like Protein.
    
 0.688
D6WPF3_TRICA
HemK methyltransferase family member 2-like Protein.
    
 0.688
D6X1Q8_TRICA
Uroporphyrinogen-III synthase-like Protein.
  
  
 0.622
D6WR64_TRICA
Delta-aminolevulinic acid dehydratase-like Protein; Belongs to the ALAD family.
  
  
 0.617
Your Current Organism:
Tribolium castaneum
NCBI taxonomy Id: 7070
Other names: T. castaneum, red flour beetle, rust-red flour beetle
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.