STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
D6WC30_TRICAMalic enzyme. (620 aa)    
Predicted Functional Partners:
D6WJB5_TRICA
Fumarate hydratase, mitochondrial-like Protein.
  
 
 0.993
A0A139WJ24
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
 0.990
A0A139WAJ1
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.962
A0A139WDM5
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.962
D6WCE5_TRICA
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.962
D6X401_TRICA
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 
 0.960
D2A083_TRICA
Malate dehydrogenase.
  
 0.952
A0A139WHG4
Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.948
D6WMM4_TRICA
Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.948
D2A663_TRICA
Malate dehydrogenase, mitochondrial-like Protein; Belongs to the LDH/MDH superfamily.
  
 0.942
Your Current Organism:
Tribolium castaneum
NCBI taxonomy Id: 7070
Other names: T. castaneum, red flour beetle, rust-red flour beetle
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.