STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Toll10Toll-7-like protein; Belongs to the Toll-like receptor family. (1321 aa)    
Predicted Functional Partners:
Spz
Spaetzle.
    
 0.634
Kra
Myd88.
    
 0.596
A0A139WC98
Calcium homeostasis endoplasmic reticulum protein-like Protein.
    
  0.526
Traf2
TNF-receptor-associated factor 2.
   
 0.525
Spz3
Spaetzle domain-containing protein.
      
 0.509
Tak1
TGF-beta activated kinase 1.
    
 0.485
Cact
Cactus.
    
 0.471
D6X3T1_TRICA
Transmembrane emp24 domain-containing protein eca-like Protein.
    
 0.459
Spz4
Spatzle 4.
      
 0.447
Serpin12
Uncharacterized protein; Belongs to the serpin family.
      
 0.446
Your Current Organism:
Tribolium castaneum
NCBI taxonomy Id: 7070
Other names: T. castaneum, red flour beetle, rust-red flour beetle
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.