STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
D6WH06_TRICAPyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (397 aa)    
Predicted Functional Partners:
D6WXB4_TRICA
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 
 0.999
D6X401_TRICA
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 
 0.999
D6W8S4_TRICA
2-oxoisovalerate dehydrogenase subunit beta, mitochondrial-like Protein.
 
 0.987
Dld
Dihydrolipoyl dehydrogenase, mitochondrial-like protein.
   
 0.978
A0A139WJ24
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
  
 
 0.937
A0A139WAJ1
Pyruvate kinase; Belongs to the pyruvate kinase family.
   
 0.935
A0A139WDM5
Pyruvate kinase; Belongs to the pyruvate kinase family.
   
 0.935
D6WCE5_TRICA
Pyruvate kinase; Belongs to the pyruvate kinase family.
   
 0.935
D6WC30_TRICA
Malic enzyme.
  
 0.927
D6WC31_TRICA
Malic enzyme.
  
 0.927
Your Current Organism:
Tribolium castaneum
NCBI taxonomy Id: 7070
Other names: T. castaneum, red flour beetle, rust-red flour beetle
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.