STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
D6WP58_TRICAIsopentenyl-diphosphate Delta-isomerase 1-like Protein. (256 aa)    
Predicted Functional Partners:
Fpps
Farnesyl pyrophosphate synthase.
  
 
 0.973
D6WD18_TRICA
Geranylgeranyl pyrophosphate synthase-like Protein; Belongs to the FPP/GGPP synthase family.
  
 
 0.929
D6WTE1_TRICA
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
  
  
 0.836
D6WE42_TRICA
Diphosphomevalonate decarboxylase.
  
 
 0.820
D6WVK3_TRICA
Alkyl transferase; Belongs to the UPP synthase family.
  
 
 0.723
A0A139WMR2
Zinc finger protein 221-like Protein.
   
 
 0.686
D2A4R0_TRICA
Mevalonate kinase.
  
 
 0.685
A0A139WIA9
3-hydroxy-3-methylglutaryl coenzyme A reductase.
 
  
 0.672
D6WSF8_TRICA
3-hydroxy-3-methylglutaryl coenzyme A reductase.
 
  
 0.672
D2A066_TRICA
Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
      0.565
Your Current Organism:
Tribolium castaneum
NCBI taxonomy Id: 7070
Other names: T. castaneum, red flour beetle, rust-red flour beetle
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.