STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
D6WRS1_TRICASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1954 aa)    
Predicted Functional Partners:
A0A139WP75
Uncharacterized protein.
   
 0.992
A0A139WER0
Sodium channel protein 60E-like Protein.
 
   
  0.941
A0A139WCP4
Uncharacterized protein.
  
0.717
D6W7C7_TRICA
WD repeat-containing protein 35-like Protein.
    
 0.647
A0A139WM23
Intraflagellar transport protein 122 homolog-like Protein.
   
 0.628
D2A3G8_TRICA
WD repeat-containing protein 19-like Protein.
    
 0.618
D6WYI0_TRICA
Intraflagellar transport protein 140 homolog-like Protein.
    
 0.618
A0A139WHE7
Voltage-dependent L-type calcium channel subunit beta-2-like Protein.
   
 0.608
D6WP19_TRICA
Uncharacterized protein.
   
 0.608
Para
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
  
  
 
0.570
Your Current Organism:
Tribolium castaneum
NCBI taxonomy Id: 7070
Other names: T. castaneum, red flour beetle, rust-red flour beetle
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.