D6WUB8_TRICA protein (Tribolium castaneum) - STRING interaction network

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D6WUB8_TRICA

2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase). (478 aa)

Predicted Functional Partners:

D6WZ76_TRICA

0.999

Dld

0.998

A0A139WI65

0.998

DHTKD1

0.998

D6WNP7_TRICA

0.990

D7EI33_TRICA

0.989

D7EI34_TRICA

0.989

D6W7D6_TRICA

0.988

D6X542_TRICA

0.987

D6W8S4_TRICA

0.981

Your Current Organism:

Tribolium castaneum

NCBI taxonomy Id: 7070
Other names: T. castaneum, red flour beetle, rust-red flour beetle

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A139WI65	D6W7D6_TRICA	A0A139WI65	D6W7D6	Putative 2-oxoglutarate dehydrogenase E1 component DHKTD1 homolog, mitochondrial-like Protein.	Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.	0.958
A0A139WI65	D6W8S4_TRICA	A0A139WI65	D6W8S4	Putative 2-oxoglutarate dehydrogenase E1 component DHKTD1 homolog, mitochondrial-like Protein.	2-oxoisovalerate dehydrogenase subunit beta, mitochondrial-like Protein.	0.865
A0A139WI65	D6WNP7_TRICA	A0A139WI65	D6WNP7	Putative 2-oxoglutarate dehydrogenase E1 component DHKTD1 homolog, mitochondrial-like Protein.	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.952
A0A139WI65	D6WUB8_TRICA	A0A139WI65	D6WUB8	Putative 2-oxoglutarate dehydrogenase E1 component DHKTD1 homolog, mitochondrial-like Protein.	2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase).	0.998
A0A139WI65	D6WZ76_TRICA	A0A139WI65	D6WZ76	Putative 2-oxoglutarate dehydrogenase E1 component DHKTD1 homolog, mitochondrial-like Protein.	Putative 2-oxoglutarate dehydrogenase E1 component DHKTD1 homolog, mitochondrial-like Protein.	0.547
A0A139WI65	D6X542_TRICA	A0A139WI65	D6X542	Putative 2-oxoglutarate dehydrogenase E1 component DHKTD1 homolog, mitochondrial-like Protein.	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).	0.863
A0A139WI65	D7EI33_TRICA	A0A139WI65	D7EI33	Putative 2-oxoglutarate dehydrogenase E1 component DHKTD1 homolog, mitochondrial-like Protein.	Dihydrolipoyl dehydrogenase-like Protein.	0.924
A0A139WI65	D7EI34_TRICA	A0A139WI65	D7EI34	Putative 2-oxoglutarate dehydrogenase E1 component DHKTD1 homolog, mitochondrial-like Protein.	Pyr_redox_2 domain-containing protein.	0.924
A0A139WI65	DHTKD1	A0A139WI65	D6WSA2	Putative 2-oxoglutarate dehydrogenase E1 component DHKTD1 homolog, mitochondrial-like Protein.	Putative 2-oxoglutarate dehydrogenase E1 component DHKTD1 homolog, mitochondrial-like Protein.	0.558
A0A139WI65	Dld	A0A139WI65	A0A139W990	Putative 2-oxoglutarate dehydrogenase E1 component DHKTD1 homolog, mitochondrial-like Protein.	Dihydrolipoyl dehydrogenase, mitochondrial-like protein.	0.924
D6W7D6_TRICA	A0A139WI65	D6W7D6	A0A139WI65	Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.	Putative 2-oxoglutarate dehydrogenase E1 component DHKTD1 homolog, mitochondrial-like Protein.	0.958
D6W7D6_TRICA	D6W8S4_TRICA	D6W7D6	D6W8S4	Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.	2-oxoisovalerate dehydrogenase subunit beta, mitochondrial-like Protein.	0.765
D6W7D6_TRICA	D6WNP7_TRICA	D6W7D6	D6WNP7	Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.999
D6W7D6_TRICA	D6WUB8_TRICA	D6W7D6	D6WUB8	Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.	2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase).	0.988
D6W7D6_TRICA	D6WZ76_TRICA	D6W7D6	D6WZ76	Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.	Putative 2-oxoglutarate dehydrogenase E1 component DHKTD1 homolog, mitochondrial-like Protein.	0.958
D6W7D6_TRICA	D6X542_TRICA	D6W7D6	D6X542	Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).	0.742
D6W7D6_TRICA	D7EI33_TRICA	D6W7D6	D7EI33	Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.	Dihydrolipoyl dehydrogenase-like Protein.	0.846
D6W7D6_TRICA	D7EI34_TRICA	D6W7D6	D7EI34	Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.	Pyr_redox_2 domain-containing protein.	0.846
D6W7D6_TRICA	DHTKD1	D6W7D6	D6WSA2	Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.	Putative 2-oxoglutarate dehydrogenase E1 component DHKTD1 homolog, mitochondrial-like Protein.	0.887
D6W7D6_TRICA	Dld	D6W7D6	A0A139W990	Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.	Dihydrolipoyl dehydrogenase, mitochondrial-like protein.	0.846