STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Fz4Frizzled 4; Belongs to the G-protein coupled receptor Fz/Smo family. (527 aa)    
Predicted Functional Partners:
Wnt11
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
  
 
 0.980
Wnt5
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
  
 
 0.980
D2A430_TRICA
Segment polarity protein dishevelled-like Protein.
    
 0.978
D2A038_TRICA
Low-density lipoprotein receptor-related protein 6-like Protein.
    
 0.967
D2A6A0_TRICA
Tyrosine-protein kinase transmembrane receptor Ror-like Protein.
    
 0.955
Bambi
BMP and activin membrane-bound inhibitor-like.
    
 0.942
D6W7I8_TRICA
Tyrosine-protein kinase Dnt-like Protein.
    
 0.930
Fz2
Frizzled 2; Belongs to the G-protein coupled receptor Fz/Smo family.
  
  
0.917
Fz
Frizzled; Belongs to the G-protein coupled receptor Fz/Smo family.
  
  
0.917
Wnt7
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
    
 0.913
Your Current Organism:
Tribolium castaneum
NCBI taxonomy Id: 7070
Other names: T. castaneum, red flour beetle, rust-red flour beetle
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.