STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
D6X1B7_TRICAFACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (712 aa)    
Predicted Functional Partners:
D6WL41_TRICA
FACT complex subunit spt16-like Protein.
   
 0.999
D6WC33_TRICA
RNA polymerase-associated protein CTR9 homolog-like Protein.
   
 0.998
D6X3J7_TRICA
Parafibromin-like Protein.
   
 0.997
A0A139WMF5
RNA polymerase II-associated factor 1 homolog-like protein.
   
 0.996
D6WFR8_TRICA
RNA polymerase-associated protein Rtf1-like Protein.
   
 0.995
D2A605_TRICA
Transcription elongation factor SPT5.
   
 0.993
D6WKU5_TRICA
Another transcription unit protein-like Protein.
   
 0.993
D6WXD8_TRICA
Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family.
   
 0.992
D6WVM1_TRICA
Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.
    
 0.986
D6WKM1_TRICA
DNA-directed RNA polymerase II subunit RPB3-like Protein.
    
 0.962
Your Current Organism:
Tribolium castaneum
NCBI taxonomy Id: 7070
Other names: T. castaneum, red flour beetle, rust-red flour beetle
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.