STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ADR32672.1Diguanylate cyclase/phosphodiesterase; COGs: COG2200 FOG: EAL domain; InterPro IPR001633: IPR000160; KEGG: nis:NIS_0004 hypothetical protein; PFAM: EAL domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein; SPTR: Diguanylate cyclase/phosphodiesterase, putative; PFAM: EAL domain; GGDEF domain. (467 aa)    
Predicted Functional Partners:
ADR34682.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014: IPR005467: IPR001789: IPR000700: IPR 006189: IPR008207: IPR001610: IPR003661: IPR003594: IPR004358:I PR013767: IPR013656; KEGG: azo:azo2482 putative hybrid sensor and regulator; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; CHASE domain protein; PAS fold domain protein; PAS fold-4 domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing [...]
  
 
 0.886
ADR34300.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660: IPR013656: IPR003661: IPR003594: IPR 001789: IPR005467: IPR000014: IPR000700: IPR004358; KEGG: ant:Arnit_0359 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; histidine kinase HAMP region domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; response regulator receiver; SPTR: Multi-sensor hybrid histidine kinase; T [...]
  
 
 0.881
ADR34173.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); COGs: COG2200 FOG: EAL domain; InterProIPR013702: IPR019494: IPR013655: IPR000160: IPR 001633: IPR000014: IPR000700: IPR001610; KEGG: pin:Ping_1203 sensor histidine kinase PAS domain-containing protein; PFAM: EAL domain protein; domain of unknown function DUF1745; FIST C domain; PAS fold-3 domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein; SPTR: Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S); [...]
 
 
 0.862
ADR32789.1
Diguanylate cyclase/phosphodiesterase with GAF sensor; COGs: COG2200 FOG: EAL domain; InterPro IPR001633: IPR000160: IPR003018; KEGG: hna:Hneap_1816 diguanylate cyclase/phosphodiesterase with GAF sensor; PFAM: EAL domain protein; GGDEF domain containing protein; GAF domain protein; SMART: EAL domain protein; GGDEF domain containing protein; SPTR: Diguanylate cyclase/phosphodiesterase with GAF sensor; PFAM: EAL domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
  
 0.847
ADR33502.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC and Chase sensor(s); COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterProIPR000014: IPR000700: IPR006189: IPR001633: IPR 000160: IPR001610: IPR013656: IPR003018: IPR002052; KEGG: rfr:Rfer_0458 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: EAL domain protein; GGDEF domain containing protein; PAS fold-4 domain protein; CHASE domain protein; GAF domain protein; SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein; PAC repeat-co [...]
 
 
 0.825
ADR34657.1
Hpt sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR001789: IPR008207: IPR003661: IPR 003594: IPR004358; KEGG: tdn:Suden_0617 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; SPTR: Sensor protein GacS; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; [...]
  
  
 0.819
ADR34287.1
COGs: COG2200 FOG: EAL domain; InterPro IPR001789: IPR000160: IPR001633; KEGG: ant:Arnit_0784 response regulator receiver modulated diguanylate cyclase/phosphodiesterase; PFAM: EAL domain protein; response regulator receiver; GGDEF domain containing protein; SMART: EAL domain protein; response regulator receiver; GGDEF domain containing protein; SPTR: Ggdef family protein; TIGRFAM: diguanylate cyclase; PFAM: EAL domain; Response regulator receiver domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
 
 0.813
ADR32886.1
Diguanylate cyclase/phosphodiesterase; COGs: COG2200 FOG: EAL domain; InterPro IPR000160: IPR001633; KEGG: nam:NAMH_0258 diguanylate cyclase/phosphodiesterase; PFAM: EAL domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein; SPTR: Diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PFAM: EAL domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
  
 0.797
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
       0.791
queF
7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
       0.791
Your Current Organism:
Sulfuricurvum kujiense
NCBI taxonomy Id: 709032
Other names: S. kujiense DSM 16994, Sulfuricurvum kujiense DSM 16994, Sulfuricurvum kujiense YK-1, Sulfuricurvum kujiense str. DSM 16994, Sulfuricurvum kujiense strain DSM 16994
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