STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADR32805.1KpsF/GutQ family protein; COGs: COG0794 sugar phosphate isomerase involved in capsule formation; InterPro IPR004800: IPR000644: IPR001347; KEGG: nis:NIS_0063 arabinose-5-phosphate isomerase; PFAM: sugar isomerase (SIS); CBS domain containing protein; PRIAM: Arabinose-5-phosphate isomerase; SMART: CBS domain containing protein; SPTR: Arabinose-5-phosphate isomerase; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain; SIS domain; TIGRFAM: KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily. (322 aa)    
Predicted Functional Partners:
kdsA
2-dehydro-3-deoxyphosphooctonate aldolase; COGs: COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; InterPro IPR006269: IPR006218; KEGG: tdn:Suden_0401 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA; SPTR: 2-dehydro-3-deoxyphosphooctonate aldolase; TIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I family; TIGRFAM: 3-deoxy-8-phosphooctulonate synthase.
 
 
 0.989
ADR34092.1
3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; COGs: COG1778 Low specificity phosphatase (HAD superfamily); InterPro IPR010023: IPR006549: IPR013200; KEGG: tdn:Suden_1079 phosphatase KdsC; PFAM: Haloacid dehalogenase domain protein hydrolase type 3; SPTR: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; hydrolase, HAD-superfamily, subfamily IIIA; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; HAD-superfamily hydrol [...]
  
 0.989
kdsB
3-deoxy-D-manno- octulosonatecytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
 
   
 0.888
ADR33160.1
Three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
 
   
 0.881
ADR35053.1
3-deoxy-D-manno- octulosonatecytidylyltransferase; COGs: COG1212 CMP-2-keto-3-deoxyoctulosonic acid synthetase; InterPro IPR004528: IPR003329; KEGG: dvl:Dvul_2642 3-deoxy-manno-octulosonate cytidylyltransferase; PFAM: acylneuraminate cytidylyltransferase; PRIAM: 3-deoxy-manno-octulosonate cytidylyltransferase; SPTR: 3-deoxy-D-manno-octulosonate cytidylyltransferase; TIGRFAM: 3-deoxy-D-manno-octulosonate cytidylyltransferase; PFAM: Cytidylyltransferase; TIGRFAM: 3-deoxy-D-manno-octulosonate cytidylyltransferase; Belongs to the KdsB family.
 
   
 0.867
lpxK
lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
 
   
 0.866
ADR32808.1
Recombination protein MgsA; COGs: COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase; InterPro IPR003959: IPR003593; KEGG: tdn:Suden_0211 recombination factor protein RarA; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; SPTR: AAA ATPase; PFAM: MgsA AAA+ ATPase C terminal; ATPase family associated with various cellular activities (AAA).
       0.817
ADR32806.1
RNA-binding S4 domain protein; COGs: COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthase; InterPro IPR018496: IPR000748: IPR002942: IPR006145; KEGG: tdn:Suden_0212 pseudouridine synthase, Rsu; PFAM: RNA-binding S4 domain protein; pseudouridine synthase; SMART: RNA-binding S4 domain protein; SPTR: Pseudouridine synthase; PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase; Belongs to the pseudouridine synthase RsuA family.
       0.816
ADR32807.1
Protein of unknown function UPF0047; COGs: COG0432 conserved hypothetical protein; InterPro IPR001602; KEGG: nis:NIS_0065 hypothetical protein; PFAM: protein of unknown function UPF0047; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised protein family UPF0047; TIGRFAM: secondary thiamine-phosphate synthase enzyme.
       0.791
ADR33690.1
lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
   
 0.784
Your Current Organism:
Sulfuricurvum kujiense
NCBI taxonomy Id: 709032
Other names: S. kujiense DSM 16994, Sulfuricurvum kujiense DSM 16994, Sulfuricurvum kujiense YK-1, Sulfuricurvum kujiense str. DSM 16994, Sulfuricurvum kujiense strain DSM 16994
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