STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rimOSSU ribosomal protein S12P methylthiotransferase; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. (438 aa)    
Predicted Functional Partners:
tilS
tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.
     
 0.829
rlmN
23S rRNA m(2)A-2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.
 
  
 0.698
ADR34179.1
COGs: COG0008 Glutamyl- and glutaminyl-tRNA synthetase; InterProIPR020058: IPR020059: IPR018027: IPR001412: IPR 020060: IPR004514; KEGG: sun:SUN_1139 glutaminyl-tRNA synthetase; PFAM: Glutamyl/glutaminyl-tRNA synthetase, class Ic, catalytic domain; Glutamyl/glutaminyl-tRNA synthetase, class Ic, anti-codon binding domain; Asn/Gln amidotransferase; SPTR: Glutaminyl-tRNA synthetase; TIGRFAM: glutaminyl-tRNA synthetase; PFAM: tRNA synthetases class I (E and Q), catalytic domain; tRNA synthetases class I (E and Q), anti-codon binding domain; GatB domain; TIGRFAM: glutaminyl-tRNA synthetase.
  
  
 0.627
ADR34222.1
COGs: COG0681 Signal peptidase I; InterPro IPR019759: IPR019758: IPR000223; KEGG: tdn:Suden_1114 peptidase S26A, signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; SPTR: Peptidase S26A, signal peptidase I; TIGRFAM: signal peptidase I; manually curated; PFAM: Peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type; Belongs to the peptidase S26 family.
  
    0.596
msrP
Oxidoreductase molybdopterin binding protein; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to [...]
       0.560
rpsG
SSU ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
  
  
 0.555
ADR32976.1
COGs: COG2717 membrane protein; InterPro IPR013130; KEGG: abu:Abu_0562 hypothetical protein; PFAM: Ferric reductase domain protein transmembrane component domain; SPTR: Conserved hypothetical membrane protein; PFAM: Ferric reductase like transmembrane component.
       0.542
ADR32977.1
HI0933 family protein; COGs: COG2081 flavoprotein; InterPro IPR004792: IPR013027; KEGG: tdn:Suden_1736 HI0933-like protein; PFAM: HI0933 family protein; SPTR: HI0933-like protein; PFAM: HI0933-like protein; TIGRFAM: flavoprotein, HI0933 family.
       0.542
rpsF
SSU ribosomal protein S6P; Binds together with S18 to 16S ribosomal RNA.
  
  
 0.539
rpsT
SSU ribosomal protein S20P; Binds directly to 16S ribosomal RNA.
  
  
 0.531
Your Current Organism:
Sulfuricurvum kujiense
NCBI taxonomy Id: 709032
Other names: S. kujiense DSM 16994, Sulfuricurvum kujiense DSM 16994, Sulfuricurvum kujiense YK-1, Sulfuricurvum kujiense str. DSM 16994, Sulfuricurvum kujiense strain DSM 16994
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