STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADR33271.1COGs: COG0294 Dihydropteroate synthase; InterPro IPR000489: IPR006390; KEGG: tdn:Suden_1647 dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS; PRIAM: Dihydropteroate synthase; SPTR: Dihydropteroate synthase; TIGRFAM: dihydropteroate synthase; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. (378 aa)    
Predicted Functional Partners:
ADR33141.1
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550: IPR002052; KEGG: sun:SUN_1040 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; SPTR:2-amino-4-hydroxy-6-hydroxymethyldihydropterid inepyrophosphokinase; TIGRFAM:2-amino-4-hydroxy-6-hydroxymethyldihydropte ridinepyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridi [...]
 
 
 0.998
ADR33104.1
COGs: COG1539 Dihydroneopterin aldolase; InterPro IPR006157; KEGG: sun:SUN_1982 hypothetical protein; PFAM: dihydroneopterin aldolase; SPTR: Putative uncharacterized protein; PFAM: Dihydroneopterin aldolase; TIGRFAM: dihydroneopterin aldolase; FolB domain.
  
 
 0.994
ADR33188.1
FolC bifunctional protein; COGs: COG0285 Folylpolyglutamate synthase; InterPro IPR001645; KEGG: tdn:Suden_1569 folylpolyglutamate synthetase; SPTR: Folylpolyglutamate synthetase; TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase middle domain; TIGRFAM: folylpolyglutamate synthase/dihydrofolate synthase.
 
 0.991
folE
COGs: COG0302 GTP cyclohydrolase I; InterPro IPR018234: IPR020602: IPR001474; KEGG: tdn:Suden_2086 GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase; PRIAM: GTP cyclohydrolase I; SPTR: GTP cyclohydrolase 1; TIGRFAM: GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I.
  
 0.980
ADR33178.1
KEGG: sun:SUN_0387 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Aminotransferase class IV.
  
 
 0.931
ADR33268.1
COGs: COG0527 Aspartokinase; InterProIPR005260: IPR001341: IPR001048: IPR002912: IPR 018042; KEGG: tdn:Suden_1650 aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; SPTR: Aspartokinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: ACT domain; Amino acid kinase family; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase; Belongs to the aspartokinase family.
     
 0.835
ADR33267.1
NUDIX hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family.
     
 0.826
ADR33269.1
KEGG: tdn:Suden_1649 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: DNA replication regulator.
       0.818
ADR33270.1
KEGG: sdl:Sdel_1375 putative DNA polymerase III delta prime subunit HolB; SPTR: DNA polymerase III delta prime subunit HolB.
  
    0.793
ADR33272.1
Transporter, CPA2 family; COGs: COG0475 Kef-type K+ transport systems membrane components; InterPro IPR006153; KEGG: wsu:WS1342 putative Na+/H+ antiporter; PFAM: sodium/hydrogen exchanger; SPTR: PUTATIVE NA+/H+ ANTIPORTER; PFAM: Sodium/hydrogen exchanger family; TC 2.A.37.
       0.773
Your Current Organism:
Sulfuricurvum kujiense
NCBI taxonomy Id: 709032
Other names: S. kujiense DSM 16994, Sulfuricurvum kujiense DSM 16994, Sulfuricurvum kujiense YK-1, Sulfuricurvum kujiense str. DSM 16994, Sulfuricurvum kujiense strain DSM 16994
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