STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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[Homology]
Score
ADR33857.1Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterPro IPR000014: IPR001633: IPR000160: IPR013767; KEGG: meh:M301_2309 diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); PFAM: EAL domain protein; GGDEF domain containing protein; PAS fold domain protein; SMART: EAL domain protein; GGDEF domain containing protein; SPTR: Diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(S); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain; G [...] (592 aa)    
Predicted Functional Partners:
ADR34682.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014: IPR005467: IPR001789: IPR000700: IPR 006189: IPR008207: IPR001610: IPR003661: IPR003594: IPR004358:I PR013767: IPR013656; KEGG: azo:azo2482 putative hybrid sensor and regulator; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; CHASE domain protein; PAS fold domain protein; PAS fold-4 domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing [...]
 
 
 0.895
ADR34300.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660: IPR013656: IPR003661: IPR003594: IPR 001789: IPR005467: IPR000014: IPR000700: IPR004358; KEGG: ant:Arnit_0359 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; histidine kinase HAMP region domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; response regulator receiver; SPTR: Multi-sensor hybrid histidine kinase; T [...]
 
 
 0.893
ADR34173.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); COGs: COG2200 FOG: EAL domain; InterProIPR013702: IPR019494: IPR013655: IPR000160: IPR 001633: IPR000014: IPR000700: IPR001610; KEGG: pin:Ping_1203 sensor histidine kinase PAS domain-containing protein; PFAM: EAL domain protein; domain of unknown function DUF1745; FIST C domain; PAS fold-3 domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein; SPTR: Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S); [...]
 
 
0.807
ADR32789.1
Diguanylate cyclase/phosphodiesterase with GAF sensor; COGs: COG2200 FOG: EAL domain; InterPro IPR001633: IPR000160: IPR003018; KEGG: hna:Hneap_1816 diguanylate cyclase/phosphodiesterase with GAF sensor; PFAM: EAL domain protein; GGDEF domain containing protein; GAF domain protein; SMART: EAL domain protein; GGDEF domain containing protein; SPTR: Diguanylate cyclase/phosphodiesterase with GAF sensor; PFAM: EAL domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
 
0.800
ADR34657.1
Hpt sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR001789: IPR008207: IPR003661: IPR 003594: IPR004358; KEGG: tdn:Suden_0617 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; SPTR: Sensor protein GacS; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; [...]
 
 
 0.796
ADR33376.1
Diguanylate cyclase/phosphodiesterase with GAF sensor; COGs: COG3899 ATPase; InterProIPR000719: IPR001633: IPR000160: IPR020635: IPR 002290: IPR019734: IPR003018: IPR017442; KEGG: npu:Npun_F2369 multi-sensor signal transduction multi-kinase; PFAM: EAL domain protein; Serine/threonine-protein kinase-like domain; GAF domain protein; GGDEF domain containing protein; SMART: EAL domain protein; serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; Tetratricopeptide repeat; GAF domain protein; GGDEF domain containing protein; SPTR: Serine/threonine kinase with GAF domai [...]
 
 
0.778
ADR34656.1
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: tdn:Suden_0616 two component transcriptional regulator; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
  
 
 0.765
ADR32810.1
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR022272: IPR004358: IPR005467: IPR001638: IPR 003594; KEGG: abu:Abu_1637 two-component sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; extracellular solute-binding protein family 3; SMART: ATP-binding region ATPase domain protein; extracellular solute-binding protein family 3; SPTR: Histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Bacterial extracellular solute-binding proteins, family 3; NMT1/THI5 like.
  
 
 0.733
ADR34739.1
Ammonium transporter; COGs: COG0004 Ammonia permease; InterPro IPR001905; KEGG: ant:Arnit_2885 ammonium transporter; PFAM: ammonium transporter; SPTR: Ammonium transporter; PFAM: Ammonium Transporter Family; TIGRFAM: ammonium transporter; TC 1.A.11.
 
      0.732
ADR33502.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC and Chase sensor(s); COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterProIPR000014: IPR000700: IPR006189: IPR001633: IPR 000160: IPR001610: IPR013656: IPR003018: IPR002052; KEGG: rfr:Rfer_0458 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: EAL domain protein; GGDEF domain containing protein; PAS fold-4 domain protein; CHASE domain protein; GAF domain protein; SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein; PAC repeat-co [...]
 
 
 
0.724
Your Current Organism:
Sulfuricurvum kujiense
NCBI taxonomy Id: 709032
Other names: S. kujiense DSM 16994, Sulfuricurvum kujiense DSM 16994, Sulfuricurvum kujiense YK-1, Sulfuricurvum kujiense str. DSM 16994, Sulfuricurvum kujiense strain DSM 16994
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