STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
ADR34121.1Hypothetical protein; InterPro IPR006121: IPR017969; KEGG: nis:NIS_0840 hypothetical protein; SPTR: Heavy metal transport/detoxification protein; PFAM: Heavy-metal-associated domain. (100 aa)    
Predicted Functional Partners:
ADR34807.1
Heavy metal translocating P-type ATPase; COGs: COG2217 Cation transport ATPase; InterProIPR018303: IPR006121: IPR006403: IPR006416: IPR 001757: IPR001877: IPR008250: IPR005834; KEGG: tdn:Suden_0576 copper-translocating P-type ATPase:heavy metal translocating P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrolase; SPTR: Copper-translocating P-type ATPase; TIGRFAM: heavy metal translocating P-type ATPase; copper-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, su [...]
  
 
 0.907
sucD
succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
   
   0.787
sucC
succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
       0.778
mdh
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
       0.731
fumC
Fumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
       0.718
ADR33718.1
InterPro IPR018638; KEGG: abu:Abu_2172 hypothetical protein; PFAM: Protein of unknown function DUF2061, membrane; SPTR: Putative uncharacterized protein; PFAM: Predicted membrane protein (DUF2061).
  
     0.662
ADR34120.1
2-oxoglutarate ferredoxin oxidoreductase, delta subunit; InterPro IPR017896: IPR017900; KEGG: tdn:Suden_1052 2-oxoglutarate-acceptor oxidoreductase subunit OorD; SPTR: 2-oxoglutarate:acceptor oxidoreductase delta subunit.
     
 0.586
ADR34798.1
Hypothetical protein; InterPro IPR008266; KEGG: tdn:Suden_0587 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Lipopolysaccharide kinase (Kdo/WaaP) family.
  
     0.561
ADR34117.1
COGs: COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase gamma subunit; InterPro IPR019752; KEGG: sun:SUN_0581 2-oxoglutarate-acceptor oxidoreductase subunit OorC; PFAM: Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; SPTR: 2-oxoglutarate ferredoxin oxidoreductase, gamma subunit; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase.
       0.550
ADR34118.1
2-oxoglutarate ferredoxin oxidoreductase, beta subunit; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: nis:NIS_0843 2-oxoglutarate-acceptor oxidoreductase subunit OorB; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; PRIAM: 2-oxoglutarate synthase; SPTR: 2-oxoglutarate ferredoxin oxidoreductase, beta subunit; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain.
       0.550
Your Current Organism:
Sulfuricurvum kujiense
NCBI taxonomy Id: 709032
Other names: S. kujiense DSM 16994, Sulfuricurvum kujiense DSM 16994, Sulfuricurvum kujiense YK-1, Sulfuricurvum kujiense str. DSM 16994, Sulfuricurvum kujiense strain DSM 16994
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