STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADR34445.1Putative PAS/PAC sensor protein; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterProIPR001789: IPR013767: IPR006674: IPR000014: IPR 000700: IPR001610: IPR003607; KEGG: abu:Abu_0453 two-component response regulator; PFAM: response regulator receiver; PAS fold domain protein; metal-dependent phosphohydrolase HD sub domain; SMART: response regulator receiver; PAS domain containing protein; PAC repeat-containing protein; metal-dependent phosphohydrolase HD region; SPTR: Response regulator receiver modulated metal dependent phosphohydrolase [...] (467 aa)    
Predicted Functional Partners:
ADR34657.1
Hpt sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR001789: IPR008207: IPR003661: IPR 003594: IPR004358; KEGG: tdn:Suden_0617 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; SPTR: Sensor protein GacS; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; [...]
 
 0.953
ADR34444.1
Integral membrane sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR003661: IPR003594: IPR001789: IPR005467: IPR 004358; KEGG: hch:HCH_00309 signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; SPTR: Signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; [...]
 
0.946
ADR34639.1
COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR000160: IPR001789; KEGG: tdn:Suden_1780 diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver; SMART: GGDEF domain containing protein; response regulator receiver; SPTR: Response regulator receiver modulated diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: Response regulator receiver domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
  
0.903
ADR33987.1
Diguanylate cyclase; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR000160: IPR001610: IPR000700; KEGG: ant:Arnit_0865 PAS/PAC sensor-containg diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; PAC repeat-containing protein; SPTR: Diguanylate cyclase with PAS/PAC sensor; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; PAS fold; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
 
    0.899
ADR34333.1
Diguanylate cyclase with PAS/PAC sensor; COGs: COG2199 FOG: GGDEF domain; InterPro IPR013767: IPR000160: IPR000014; KEGG: dps:DP2126 hypothetical protein; PFAM: GGDEF domain containing protein; PAS fold domain protein; SMART: GGDEF domain containing protein; PAS domain containing protein; SPTR: Ggdef/pas/pac-domain containing protein; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain.
 
 
 0.870
ADR34621.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014: IPR005467: IPR003661: IPR003594: IPR 004358: IPR013767; KEGG: tdn:Suden_1926 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: Sensory box sensor histidine kinase/response regulator; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A ( [...]
 
0.854
ADR33079.1
Diguanylate cyclase; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: pin:Ping_1880 diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; SPTR: Diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
    0.835
ADR34682.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014: IPR005467: IPR001789: IPR000700: IPR 006189: IPR008207: IPR001610: IPR003661: IPR003594: IPR004358:I PR013767: IPR013656; KEGG: azo:azo2482 putative hybrid sensor and regulator; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; CHASE domain protein; PAS fold domain protein; PAS fold-4 domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing [...]
 
 0.824
ADR33972.1
Diguanylate cyclase; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160: IPR000644; KEGG: tbd:Tbd_1953 diguanylate cyclase; PFAM: GGDEF domain containing protein; CBS domain containing protein; SMART: GGDEF domain containing protein; SPTR: Diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: CBS domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
 
  
 0.821
ADR33289.1
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR001789: IPR003661: IPR003594: IPR 004358; KEGG: sun:SUN_1842 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Sensor histidine kinase/response regulator; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain.
 
0.799
Your Current Organism:
Sulfuricurvum kujiense
NCBI taxonomy Id: 709032
Other names: S. kujiense DSM 16994, Sulfuricurvum kujiense DSM 16994, Sulfuricurvum kujiense YK-1, Sulfuricurvum kujiense str. DSM 16994, Sulfuricurvum kujiense strain DSM 16994
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.