node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADR33345.1 | ADR34591.1 | Sulku_0679 | Sulku_1931 | Heat shock protein Hsp20; COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068; KEGG: tcx:Tcr_2022 heat shock protein HSP20; PFAM: heat shock protein Hsp20; SPTR: Heat shock protein Hsp20; PFAM: Hsp20/alpha crystallin family; Belongs to the small heat shock protein (HSP20) family. | ATP-dependent Clp protease, ATP-binding subunit clpA; COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR013461: IPR018062: IPR001270: IPR003593: IPR 004176: IPR003959: IPR013093: IPR019489; KEGG: nis:NIS_0380 ATP-dependent Clp protease, ATP-binding subunit ClpA; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; Clp domain protein; Clp ATPase-like; SMART: AAA ATPase; SPTR: ATP-dependent Clp protease ATP-binding subunit ClpA; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA domain (Cdc48 subfamily); Clp amino terminal [...] | 0.711 |
ADR33345.1 | dnaK | Sulku_0679 | Sulku_0381 | Heat shock protein Hsp20; COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068; KEGG: tcx:Tcr_2022 heat shock protein HSP20; PFAM: heat shock protein Hsp20; SPTR: Heat shock protein Hsp20; PFAM: Hsp20/alpha crystallin family; Belongs to the small heat shock protein (HSP20) family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.662 |
ADR33345.1 | grpE | Sulku_0679 | Sulku_0380 | Heat shock protein Hsp20; COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068; KEGG: tcx:Tcr_2022 heat shock protein HSP20; PFAM: heat shock protein Hsp20; SPTR: Heat shock protein Hsp20; PFAM: Hsp20/alpha crystallin family; Belongs to the small heat shock protein (HSP20) family. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.568 |
ADR33345.1 | htpG | Sulku_0679 | Sulku_1106 | Heat shock protein Hsp20; COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068; KEGG: tcx:Tcr_2022 heat shock protein HSP20; PFAM: heat shock protein Hsp20; SPTR: Heat shock protein Hsp20; PFAM: Hsp20/alpha crystallin family; Belongs to the small heat shock protein (HSP20) family. | Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity. | 0.634 |
ADR33943.1 | ADR34591.1 | Sulku_1280 | Sulku_1931 | Heat shock protein Hsp20; COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068; KEGG: ant:Arnit_3106 heat shock protein HSP20; PFAM: heat shock protein Hsp20; SPTR: Heat shock protein Hsp20; PFAM: Hsp20/alpha crystallin family; Belongs to the small heat shock protein (HSP20) family. | ATP-dependent Clp protease, ATP-binding subunit clpA; COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR013461: IPR018062: IPR001270: IPR003593: IPR 004176: IPR003959: IPR013093: IPR019489; KEGG: nis:NIS_0380 ATP-dependent Clp protease, ATP-binding subunit ClpA; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; Clp domain protein; Clp ATPase-like; SMART: AAA ATPase; SPTR: ATP-dependent Clp protease ATP-binding subunit ClpA; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA domain (Cdc48 subfamily); Clp amino terminal [...] | 0.711 |
ADR33943.1 | dnaK | Sulku_1280 | Sulku_0381 | Heat shock protein Hsp20; COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068; KEGG: ant:Arnit_3106 heat shock protein HSP20; PFAM: heat shock protein Hsp20; SPTR: Heat shock protein Hsp20; PFAM: Hsp20/alpha crystallin family; Belongs to the small heat shock protein (HSP20) family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.662 |
ADR33943.1 | grpE | Sulku_1280 | Sulku_0380 | Heat shock protein Hsp20; COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068; KEGG: ant:Arnit_3106 heat shock protein HSP20; PFAM: heat shock protein Hsp20; SPTR: Heat shock protein Hsp20; PFAM: Hsp20/alpha crystallin family; Belongs to the small heat shock protein (HSP20) family. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.568 |
ADR33943.1 | htpG | Sulku_1280 | Sulku_1106 | Heat shock protein Hsp20; COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068; KEGG: ant:Arnit_3106 heat shock protein HSP20; PFAM: heat shock protein Hsp20; SPTR: Heat shock protein Hsp20; PFAM: Hsp20/alpha crystallin family; Belongs to the small heat shock protein (HSP20) family. | Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity. | 0.634 |
ADR34591.1 | ADR33345.1 | Sulku_1931 | Sulku_0679 | ATP-dependent Clp protease, ATP-binding subunit clpA; COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR013461: IPR018062: IPR001270: IPR003593: IPR 004176: IPR003959: IPR013093: IPR019489; KEGG: nis:NIS_0380 ATP-dependent Clp protease, ATP-binding subunit ClpA; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; Clp domain protein; Clp ATPase-like; SMART: AAA ATPase; SPTR: ATP-dependent Clp protease ATP-binding subunit ClpA; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA domain (Cdc48 subfamily); Clp amino terminal [...] | Heat shock protein Hsp20; COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068; KEGG: tcx:Tcr_2022 heat shock protein HSP20; PFAM: heat shock protein Hsp20; SPTR: Heat shock protein Hsp20; PFAM: Hsp20/alpha crystallin family; Belongs to the small heat shock protein (HSP20) family. | 0.711 |
ADR34591.1 | ADR33943.1 | Sulku_1931 | Sulku_1280 | ATP-dependent Clp protease, ATP-binding subunit clpA; COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR013461: IPR018062: IPR001270: IPR003593: IPR 004176: IPR003959: IPR013093: IPR019489; KEGG: nis:NIS_0380 ATP-dependent Clp protease, ATP-binding subunit ClpA; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; Clp domain protein; Clp ATPase-like; SMART: AAA ATPase; SPTR: ATP-dependent Clp protease ATP-binding subunit ClpA; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA domain (Cdc48 subfamily); Clp amino terminal [...] | Heat shock protein Hsp20; COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068; KEGG: ant:Arnit_3106 heat shock protein HSP20; PFAM: heat shock protein Hsp20; SPTR: Heat shock protein Hsp20; PFAM: Hsp20/alpha crystallin family; Belongs to the small heat shock protein (HSP20) family. | 0.711 |
ADR34591.1 | aat | Sulku_1931 | Sulku_1930 | ATP-dependent Clp protease, ATP-binding subunit clpA; COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR013461: IPR018062: IPR001270: IPR003593: IPR 004176: IPR003959: IPR013093: IPR019489; KEGG: nis:NIS_0380 ATP-dependent Clp protease, ATP-binding subunit ClpA; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; Clp domain protein; Clp ATPase-like; SMART: AAA ATPase; SPTR: ATP-dependent Clp protease ATP-binding subunit ClpA; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA domain (Cdc48 subfamily); Clp amino terminal [...] | leucyl/phenylalanyl-tRNA/protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. | 0.845 |
ADR34591.1 | clpP | Sulku_1931 | Sulku_1515 | ATP-dependent Clp protease, ATP-binding subunit clpA; COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR013461: IPR018062: IPR001270: IPR003593: IPR 004176: IPR003959: IPR013093: IPR019489; KEGG: nis:NIS_0380 ATP-dependent Clp protease, ATP-binding subunit ClpA; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; Clp domain protein; Clp ATPase-like; SMART: AAA ATPase; SPTR: ATP-dependent Clp protease ATP-binding subunit ClpA; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA domain (Cdc48 subfamily); Clp amino terminal [...] | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.887 |
ADR34591.1 | clpP-2 | Sulku_1931 | Sulku_2526 | ATP-dependent Clp protease, ATP-binding subunit clpA; COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR013461: IPR018062: IPR001270: IPR003593: IPR 004176: IPR003959: IPR013093: IPR019489; KEGG: nis:NIS_0380 ATP-dependent Clp protease, ATP-binding subunit ClpA; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; Clp domain protein; Clp ATPase-like; SMART: AAA ATPase; SPTR: ATP-dependent Clp protease ATP-binding subunit ClpA; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA domain (Cdc48 subfamily); Clp amino terminal [...] | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.887 |
ADR34591.1 | clpS | Sulku_1931 | Sulku_1932 | ATP-dependent Clp protease, ATP-binding subunit clpA; COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR013461: IPR018062: IPR001270: IPR003593: IPR 004176: IPR003959: IPR013093: IPR019489; KEGG: nis:NIS_0380 ATP-dependent Clp protease, ATP-binding subunit ClpA; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; Clp domain protein; Clp ATPase-like; SMART: AAA ATPase; SPTR: ATP-dependent Clp protease ATP-binding subunit ClpA; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA domain (Cdc48 subfamily); Clp amino terminal [...] | ATP-dependent Clp protease adaptor protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. | 0.989 |
ADR34591.1 | dnaJ | Sulku_1931 | Sulku_1390 | ATP-dependent Clp protease, ATP-binding subunit clpA; COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR013461: IPR018062: IPR001270: IPR003593: IPR 004176: IPR003959: IPR013093: IPR019489; KEGG: nis:NIS_0380 ATP-dependent Clp protease, ATP-binding subunit ClpA; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; Clp domain protein; Clp ATPase-like; SMART: AAA ATPase; SPTR: ATP-dependent Clp protease ATP-binding subunit ClpA; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA domain (Cdc48 subfamily); Clp amino terminal [...] | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.754 |
ADR34591.1 | dnaK | Sulku_1931 | Sulku_0381 | ATP-dependent Clp protease, ATP-binding subunit clpA; COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR013461: IPR018062: IPR001270: IPR003593: IPR 004176: IPR003959: IPR013093: IPR019489; KEGG: nis:NIS_0380 ATP-dependent Clp protease, ATP-binding subunit ClpA; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; Clp domain protein; Clp ATPase-like; SMART: AAA ATPase; SPTR: ATP-dependent Clp protease ATP-binding subunit ClpA; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA domain (Cdc48 subfamily); Clp amino terminal [...] | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.961 |
ADR34591.1 | grpE | Sulku_1931 | Sulku_0380 | ATP-dependent Clp protease, ATP-binding subunit clpA; COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR013461: IPR018062: IPR001270: IPR003593: IPR 004176: IPR003959: IPR013093: IPR019489; KEGG: nis:NIS_0380 ATP-dependent Clp protease, ATP-binding subunit ClpA; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; Clp domain protein; Clp ATPase-like; SMART: AAA ATPase; SPTR: ATP-dependent Clp protease ATP-binding subunit ClpA; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA domain (Cdc48 subfamily); Clp amino terminal [...] | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.840 |
ADR34591.1 | htpG | Sulku_1931 | Sulku_1106 | ATP-dependent Clp protease, ATP-binding subunit clpA; COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR013461: IPR018062: IPR001270: IPR003593: IPR 004176: IPR003959: IPR013093: IPR019489; KEGG: nis:NIS_0380 ATP-dependent Clp protease, ATP-binding subunit ClpA; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; Clp domain protein; Clp ATPase-like; SMART: AAA ATPase; SPTR: ATP-dependent Clp protease ATP-binding subunit ClpA; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA domain (Cdc48 subfamily); Clp amino terminal [...] | Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity. | 0.722 |
aat | ADR34591.1 | Sulku_1930 | Sulku_1931 | leucyl/phenylalanyl-tRNA/protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. | ATP-dependent Clp protease, ATP-binding subunit clpA; COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR013461: IPR018062: IPR001270: IPR003593: IPR 004176: IPR003959: IPR013093: IPR019489; KEGG: nis:NIS_0380 ATP-dependent Clp protease, ATP-binding subunit ClpA; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; Clp domain protein; Clp ATPase-like; SMART: AAA ATPase; SPTR: ATP-dependent Clp protease ATP-binding subunit ClpA; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA domain (Cdc48 subfamily); Clp amino terminal [...] | 0.845 |
aat | clpS | Sulku_1930 | Sulku_1932 | leucyl/phenylalanyl-tRNA/protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. | ATP-dependent Clp protease adaptor protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. | 0.957 |