STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADR34804.1ADP-glyceromanno-heptose 6-epimerase precursor; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR011912: IPR001509; KEGG: tdn:Suden_0579 ADP-L-glycero-D-manno-heptose-6-epimerase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: ADP-glyceromanno-heptose 6-epimerase; TIGRFAM: ADP-L-glycero-D-manno-heptose-6-epimerase; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: ADP-L-glycero-D-manno-heptose-6-epimerase. (336 aa)    
Predicted Functional Partners:
hldE
D-alpha,beta-D-heptose 7-phosphate 1-kinase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family.
 
 
 0.990
ADR32870.1
COGs: COG0199 Ribosomal protein S14; InterPro IPR018271: IPR001209; KEGG: tdn:Suden_0299 30S ribosomal protein S14; PFAM: ribosomal protein S14; SPTR: 30S ribosomal protein S14 type Z; manually curated; PFAM: Ribosomal protein S14p/S29e.
   
  0.860
rpsS
SSU ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
   
  0.859
rpsL
SSU ribosomal protein S12P; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
   
 0.847
rpsC
SSU ribosomal protein S3P; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
   
 0.837
rpsQ
SSU ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
   
  0.835
rpsH
SSU ribosomal protein S8P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.
   
 0.830
rpsE
SSU ribosomal protein S5P; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.
   
 0.829
ADR32858.1
COGs: COG0088 Ribosomal protein L4; InterPro IPR002136; KEGG: tdn:Suden_0287 50S ribosomal protein L4; PFAM: ribosomal protein L4/L1e; SPTR: 50S ribosomal protein L4; PFAM: Ribosomal protein L4/L1 family.
   
  0.823
rpsO
SSU ribosomal protein S15P; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
   
  0.820
Your Current Organism:
Sulfuricurvum kujiense
NCBI taxonomy Id: 709032
Other names: S. kujiense DSM 16994, Sulfuricurvum kujiense DSM 16994, Sulfuricurvum kujiense YK-1, Sulfuricurvum kujiense str. DSM 16994, Sulfuricurvum kujiense strain DSM 16994
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