STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PI3KPI3K protein; Pi3k. (398 aa)    
Predicted Functional Partners:
H9J086_BOMMO
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
    
 0.999
Bras1
Ras oncoprotein.
    
 0.951
H9IVA3_BOMMO
Receptor protein-tyrosine kinase.
    
 0.950
H9IVI8_BOMMO
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
     
 0.950
H9JHS3_BOMMO
Uncharacterized protein.
    
 0.942
PLCg
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
    
 0.937
H9JCB3_BOMMO
Phosphatidylinositol 3-kinase catalytic subunit type 3.
     
 0.935
DRK
Uncharacterized protein.
    
 0.935
H9JCP5_BOMMO
IPPc domain-containing protein.
    
 0.924
H9J949_BOMMO
Rho-GAP domain-containing protein.
    
 0.923
Your Current Organism:
Bombyx mori
NCBI taxonomy Id: 7091
Other names: B. mori, domestic silkworm, silk moth, silkworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.