STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLCb4Phosphoinositide phospholipase C. (935 aa)    
Predicted Functional Partners:
PLCg
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
     
0.938
PLCb1
Phosphoinositide phospholipase C.
  
 
0.932
H9JCI7_BOMMO
DAGKa domain-containing protein.
     
 0.921
H9JCW5_BOMMO
Kinase; Belongs to the inositol phosphokinase (IPK) family.
    
 0.921
H9JVN4_BOMMO
Diacylglycerol kinase.
     
 0.919
Cpkc
Non-specific serine/threonine protein kinase.
   
 
 0.919
H9J7P5_BOMMO
Inositol-1-monophosphatase.
     
 0.914
H9JEN9_BOMMO
PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family.
     
 0.913
H9JTG6_BOMMO
Uncharacterized protein.
     
 0.910
cna
Serine/threonine-protein phosphatase.
    
 0.910
Your Current Organism:
Bombyx mori
NCBI taxonomy Id: 7091
Other names: B. mori, domestic silkworm, silk moth, silkworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.