STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A4Actin, cytoplasmic A4; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Multiple isoforms are involved in various cellular functions such as cytoskeleton structure, cell mobility, chromosome movement and muscle contraction. (376 aa)    
Predicted Functional Partners:
H9J1R7_BOMMO
Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
 0.922
H9JLD4_BOMMO
Uncharacterized protein.
     
  0.900
H9JBT4_BOMMO
MPN domain-containing protein.
    
 0.867
H9JJV4_BOMMO
Uncharacterized protein; Belongs to the actin family.
    
0.732
H9JK24_BOMMO
Uncharacterized protein.
   
 0.716
H9JHX1_BOMMO
Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily.
    
 0.709
H9IS56_BOMMO
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
  
0.702
H9IXD8_BOMMO
Uncharacterized protein; Belongs to the actin family.
   
0.696
H9JKE8_BOMMO
Uncharacterized protein; Belongs to the actin family.
    
0.693
H9IYP5_BOMMO
Uncharacterized protein.
   
 0.668
Your Current Organism:
Bombyx mori
NCBI taxonomy Id: 7091
Other names: B. mori, domestic silkworm, silk moth, silkworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.