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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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co-expression
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gene co-occurrence
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[Homology]
Score
CSIRO_0066Putative acetolactate synthase large subunit; Belongs to the TPP enzyme family. (564 aa)    
Predicted Functional Partners:
CSIRO_4016
Acetolactate synthase small subunit.
 
 0.986
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
 
 0.974
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
 
 0.904
CSIRO_4017
Acetolactate synthase large subunit.
  
  
 
0.883
CSIRO_4180
Glyoxylate carboligase; Belongs to the TPP enzyme family.
  
  
 
0.879
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
 
 
 0.876
CSIRO_4176
Putative oxalyl-CoA decarboxylase; Belongs to the TPP enzyme family.
  
  
 
0.871
CSIRO_2662
NAD-dependent malic enzyme.
  
 0.870
CSIRO_2716
Tartrate dehydrogenase/ tartrate decarboxylase/ D-malic enzyme; Bifunctional.
 
 0.851
ilvD-2
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
 
 
 0.825
Your Current Organism:
Bradyrhizobiaceae bacterium SG6C
NCBI taxonomy Id: 709797
Other names: B. bacterium SG-6C, Bradyrhizobiaceae bacterium SG-6C
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