Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
CSIRO_0168L-lactate dehydrogenase. (385 aa)    
Predicted Functional Partners:
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.888
CSIRO_3947
Fe-S protein.
  
 0.885
CSIRO_3945
Serine--glyoxylate aminotransferase.
  
 0.881
CSIRO_4043
D-Lactate dehydrogenase, cytochrome c-dependent.
 
 0.861
CSIRO_2662
NAD-dependent malic enzyme.
    
 0.860
CSIRO_0387
Pyruvate kinase; Belongs to the pyruvate kinase family.
   
 
 0.838
CSIRO_1776
Pyruvate-phosphate dikinase; Belongs to the PEP-utilizing enzyme family.
     
 0.796
CSIRO_3979
Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
     
 0.796
CSIRO_2812
Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
    
 0.788
CSIRO_4016
Acetolactate synthase small subunit.
  
 
  0.787
Your Current Organism:
Bradyrhizobiaceae bacterium SG6C
NCBI taxonomy Id: 709797
Other names: B. bacterium SG-6C, Bradyrhizobiaceae bacterium SG-6C
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