Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CSIRO_0628Hypothetical protein. (703 aa)    
Predicted Functional Partners:
CSIRO_0629
Hypothetical protein.
       0.831
CSIRO_1375
Acetyl-coenzyme A synthetase.
 
  
 0.806
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
 
  
 0.799
CSIRO_2812
Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 
  0.789
CSIRO_0682
acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
   
 
  0.776
CSIRO_1306
3-ketoacyl-CoA thiolase/ acetyl-CoA acetyltransferase; Bifunctional; Belongs to the thiolase-like superfamily. Thiolase family.
   
 
  0.776
CSIRO_2533
acetyl-CoA C-acyltransferase/ acetyl-CoA acetyltransferase; Bifunctional; Belongs to the thiolase-like superfamily. Thiolase family.
   
 
  0.776
CSIRO_3432
Indolepyruvate ferredoxin oxidoreductase.
   
 0.772
CSIRO_3979
Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
     
 0.772
CSIRO_1698
Isocitrate lyase.
     
 0.770
Your Current Organism:
Bradyrhizobiaceae bacterium SG6C
NCBI taxonomy Id: 709797
Other names: B. bacterium SG-6C, Bradyrhizobiaceae bacterium SG-6C
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