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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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glnDUridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. (928 aa)    
Predicted Functional Partners:
CSIRO_3203
Nitrogen regulatory protein; Belongs to the P(II) protein family.
 
 
 0.934
CSIRO_0963
Nitrogen regulatory protein P-II; Belongs to the P(II) protein family.
 
 
 0.860
CSIRO_0961
Nitrogen regulatory protein P-II; Belongs to the P(II) protein family.
 
 
 0.859
glnE
Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...]
 
   
 0.784
CSIRO_0705
Hypothetical protein.
       0.773
CSIRO_2980
Nitrogen regulation protein NR(II).
  
 
 
 0.629
CSIRO_0704
Hypothetical protein.
       0.608
CSIRO_0268
Glutamate synthase (NADPH) large chain.
     
 0.594
ntrC
Nitrogen assimilation regulatory protein; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.
  
   
 0.516
CSIRO_1715
tRNA nucleotidyltransferase; Bifunctional; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
     
  0.492
Your Current Organism:
Bradyrhizobiaceae bacterium SG6C
NCBI taxonomy Id: 709797
Other names: B. bacterium SG-6C, Bradyrhizobiaceae bacterium SG-6C
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