Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (287 aa)    
Predicted Functional Partners:
CSIRO_2822
Exodeoxyribonuclease III.
 
 0.978
CSIRO_0956
Exodeoxyribonuclease III.
  
 0.847
CSIRO_0744
Exodeoxyribonuclease III.
  
 0.791
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 
 0.763
CSIRO_1275
methylated-DNA--protein-cysteine methyltransferase.
 
 
 
 0.732
mutL
DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
 
 
 0.708
CSIRO_0880
Hypothetical protein.
       0.697
CSIRO_0881
methylated-DNA--protein-cysteine methyltransferase.
 
   
 0.634
CSIRO_1742
A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.
    
 0.584
CSIRO_1765
Bifunctional; octaprenyl-diphosphate synthase/ dimethylallyltransferase/ geranyltranstransferase (farnesyldiphosphate synthase)/ geranylgeranyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family.
 
    0.559
Your Current Organism:
Bradyrhizobiaceae bacterium SG6C
NCBI taxonomy Id: 709797
Other names: B. bacterium SG-6C, Bradyrhizobiaceae bacterium SG-6C
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