| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CSIRO_1448 | CSIRO_1450 | CSIRO_1448 | CSIRO_1450 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.994 |
| CSIRO_1448 | CSIRO_2876 | CSIRO_1448 | CSIRO_2876 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.820 |
| CSIRO_1448 | CSIRO_3008 | CSIRO_1448 | CSIRO_3008 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cysteine synthase B. | 0.820 |
| CSIRO_1448 | CSIRO_3135 | CSIRO_1448 | CSIRO_3135 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Homoserine dehydrogenase. | 0.892 |
| CSIRO_1448 | CSIRO_3597 | CSIRO_1448 | CSIRO_3597 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Serine acetyltransferase. | 0.818 |
| CSIRO_1448 | CSIRO_3612 | CSIRO_1448 | CSIRO_3612 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase. | 0.916 |
| CSIRO_1448 | CSIRO_3908 | CSIRO_1448 | CSIRO_3908 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | vitamin-B12 independent methionine synthase. | 0.916 |
| CSIRO_1448 | metE | CSIRO_1448 | CSIRO_0521 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.916 |
| CSIRO_1448 | metXA | CSIRO_1448 | CSIRO_1594 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. | 0.898 |
| CSIRO_1448 | metZ | CSIRO_1448 | CSIRO_1266 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | O-acetylhomoserine sulfhydrylase/ O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.953 |
| CSIRO_1450 | CSIRO_1448 | CSIRO_1450 | CSIRO_1448 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.994 |
| CSIRO_1450 | CSIRO_2876 | CSIRO_1450 | CSIRO_2876 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.460 |
| CSIRO_1450 | CSIRO_3008 | CSIRO_1450 | CSIRO_3008 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | Cysteine synthase B. | 0.460 |
| CSIRO_1450 | CSIRO_3135 | CSIRO_1450 | CSIRO_3135 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | Homoserine dehydrogenase. | 0.838 |
| CSIRO_1450 | CSIRO_3612 | CSIRO_1450 | CSIRO_3612 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase. | 0.924 |
| CSIRO_1450 | CSIRO_3908 | CSIRO_1450 | CSIRO_3908 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | vitamin-B12 independent methionine synthase. | 0.911 |
| CSIRO_1450 | metE | CSIRO_1450 | CSIRO_0521 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.937 |
| CSIRO_1450 | metZ | CSIRO_1450 | CSIRO_1266 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | O-acetylhomoserine sulfhydrylase/ O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.891 |
| CSIRO_2876 | CSIRO_1448 | CSIRO_2876 | CSIRO_1448 | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.820 |
| CSIRO_2876 | CSIRO_1450 | CSIRO_2876 | CSIRO_1450 | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.460 |