STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
CSIRO_1512Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. (478 aa)    
Predicted Functional Partners:
CSIRO_2169
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
 0.998
CSIRO_1514
Sulfite reductase (NADPH) hemoprotein beta-component.
 
 
 0.996
CSIRO_1516
Phosphoadenylyl-sulfate reductase/ adenylyl-sulfate reductase; Reduction of activated sulfate into sulfite.
 
  
 0.993
CSIRO_2919
Ferredoxin--nitrite reductase; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
 
 0.987
cysC
Sulfate adenylyltransferase subunit 1/ adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate.
 
  
 0.984
CSIRO_1511
Sulfate adenylyltransferase subunit 2.
 
  
 0.981
CSIRO_3304
Porphobilinogen synthase; Belongs to the ALAD family.
 
 
 0.961
CSIRO_1513
Hypothetical protein.
  
  
 0.904
CSIRO_3914
uroporphyrinogen-III methyltransferase/ uroporphyrinogen-III synthase; Bifunctional.
 
 
 0.902
CSIRO_1976
Hypothetical protein.
  
  
 0.885
Your Current Organism:
Bradyrhizobiaceae bacterium SG6C
NCBI taxonomy Id: 709797
Other names: B. bacterium SG-6C, Bradyrhizobiaceae bacterium SG-6C
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