| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CSIRO_1351 | queD | CSIRO_1351 | CSIRO_1719 | Thioredoxin reductase. | Queuosine biosynthesis QueD. | 0.552 |
| CSIRO_2330 | CSIRO_2331 | CSIRO_2330 | CSIRO_2331 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.999 |
| CSIRO_2330 | folE | CSIRO_2330 | CSIRO_3575 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | GTP cyclohydrolase Itype 1. | 0.998 |
| CSIRO_2330 | queD | CSIRO_2330 | CSIRO_1719 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | Queuosine biosynthesis QueD. | 0.615 |
| CSIRO_2331 | CSIRO_2330 | CSIRO_2331 | CSIRO_2330 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | 0.999 |
| CSIRO_2331 | folE | CSIRO_2331 | CSIRO_3575 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | GTP cyclohydrolase Itype 1. | 0.986 |
| CSIRO_2331 | queD | CSIRO_2331 | CSIRO_1719 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Queuosine biosynthesis QueD. | 0.639 |
| cysS | queD | CSIRO_2459 | CSIRO_1719 | cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | Queuosine biosynthesis QueD. | 0.545 |
| folE | CSIRO_2330 | CSIRO_3575 | CSIRO_2330 | GTP cyclohydrolase Itype 1. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | 0.998 |
| folE | CSIRO_2331 | CSIRO_3575 | CSIRO_2331 | GTP cyclohydrolase Itype 1. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.986 |
| folE | queC | CSIRO_3575 | CSIRO_2972 | GTP cyclohydrolase Itype 1. | Queuosine biosynthesis ATPase QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.457 |
| folE | queD | CSIRO_3575 | CSIRO_1719 | GTP cyclohydrolase Itype 1. | Queuosine biosynthesis QueD. | 0.896 |
| folE | queE | CSIRO_3575 | CSIRO_1720 | GTP cyclohydrolase Itype 1. | Queuosine Biosynthesis QueE; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.633 |
| folE | queF | CSIRO_3575 | CSIRO_2805 | GTP cyclohydrolase Itype 1. | NADPH dependent reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.448 |
| hemF | queD | CSIRO_1718 | CSIRO_1719 | Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | Queuosine biosynthesis QueD. | 0.826 |
| hemF | queE | CSIRO_1718 | CSIRO_1720 | Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | Queuosine Biosynthesis QueE; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.745 |
| hemF | trmL | CSIRO_1718 | CSIRO_1721 | Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | tRNA (cytosine34-2'-O-)-methyltransferase; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. | 0.905 |
| queC | folE | CSIRO_2972 | CSIRO_3575 | Queuosine biosynthesis ATPase QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | GTP cyclohydrolase Itype 1. | 0.457 |
| queC | queD | CSIRO_2972 | CSIRO_1719 | Queuosine biosynthesis ATPase QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Queuosine biosynthesis QueD. | 0.968 |
| queC | queE | CSIRO_2972 | CSIRO_1720 | Queuosine biosynthesis ATPase QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Queuosine Biosynthesis QueE; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.994 |