| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CSIRO_1448 | CSIRO_1798 | CSIRO_1448 | CSIRO_1798 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | GDP-mannose mannosyl hydrolase; Belongs to the Nudix hydrolase family. | 0.702 |
| CSIRO_1448 | CSIRO_2365 | CSIRO_1448 | CSIRO_2365 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Sensory box histidine kinase/response regulator. | 0.720 |
| CSIRO_1448 | gcvP | CSIRO_1448 | CSIRO_3708 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.860 |
| CSIRO_1448 | guaA | CSIRO_1448 | CSIRO_2557 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.496 |
| CSIRO_1448 | tal | CSIRO_1448 | CSIRO_2102 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Transaldolase/ glucose-6-phosphate isomerase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the GPI family. | 0.432 |
| CSIRO_1798 | CSIRO_1448 | CSIRO_1798 | CSIRO_1448 | GDP-mannose mannosyl hydrolase; Belongs to the Nudix hydrolase family. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.702 |
| CSIRO_1798 | CSIRO_1799 | CSIRO_1798 | CSIRO_1799 | GDP-mannose mannosyl hydrolase; Belongs to the Nudix hydrolase family. | Hypothetical protein. | 0.800 |
| CSIRO_1798 | CSIRO_1808 | CSIRO_1798 | CSIRO_1808 | GDP-mannose mannosyl hydrolase; Belongs to the Nudix hydrolase family. | 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.668 |
| CSIRO_1798 | CSIRO_2365 | CSIRO_1798 | CSIRO_2365 | GDP-mannose mannosyl hydrolase; Belongs to the Nudix hydrolase family. | Sensory box histidine kinase/response regulator. | 0.688 |
| CSIRO_1798 | CSIRO_3740 | CSIRO_1798 | CSIRO_3740 | GDP-mannose mannosyl hydrolase; Belongs to the Nudix hydrolase family. | Aerobic fumarate hydratase class 1; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.704 |
| CSIRO_1798 | CSIRO_4286 | CSIRO_1798 | CSIRO_4286 | GDP-mannose mannosyl hydrolase; Belongs to the Nudix hydrolase family. | Adenylate cyclase. | 0.667 |
| CSIRO_1798 | gcvP | CSIRO_1798 | CSIRO_3708 | GDP-mannose mannosyl hydrolase; Belongs to the Nudix hydrolase family. | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.767 |
| CSIRO_1798 | guaA | CSIRO_1798 | CSIRO_2557 | GDP-mannose mannosyl hydrolase; Belongs to the Nudix hydrolase family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.662 |
| CSIRO_1798 | nadE | CSIRO_1798 | CSIRO_2456 | GDP-mannose mannosyl hydrolase; Belongs to the Nudix hydrolase family. | NAD synthetase/ Glutamine amidotransferase chain of NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.798 |
| CSIRO_1798 | tal | CSIRO_1798 | CSIRO_2102 | GDP-mannose mannosyl hydrolase; Belongs to the Nudix hydrolase family. | Transaldolase/ glucose-6-phosphate isomerase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the GPI family. | 0.704 |
| CSIRO_1799 | CSIRO_1798 | CSIRO_1799 | CSIRO_1798 | Hypothetical protein. | GDP-mannose mannosyl hydrolase; Belongs to the Nudix hydrolase family. | 0.800 |
| CSIRO_1808 | CSIRO_1798 | CSIRO_1808 | CSIRO_1798 | 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | GDP-mannose mannosyl hydrolase; Belongs to the Nudix hydrolase family. | 0.668 |
| CSIRO_1808 | CSIRO_2365 | CSIRO_1808 | CSIRO_2365 | 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | Sensory box histidine kinase/response regulator. | 0.847 |
| CSIRO_1808 | CSIRO_4286 | CSIRO_1808 | CSIRO_4286 | 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | Adenylate cyclase. | 0.770 |
| CSIRO_1808 | guaA | CSIRO_1808 | CSIRO_2557 | 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.628 |