| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CSIRO_0234 | CSIRO_1941 | CSIRO_0234 | CSIRO_1941 | Molybdopterin converting factor subunit 1. | SirA-like protein; Belongs to the sulfur carrier protein TusA family. | 0.697 |
| CSIRO_0234 | CSIRO_2123 | CSIRO_0234 | CSIRO_2123 | Molybdopterin converting factor subunit 1. | Sulfide dehydrogenase flavoprotein chain precursor. | 0.416 |
| CSIRO_0234 | CSIRO_3158 | CSIRO_0234 | CSIRO_3158 | Molybdopterin converting factor subunit 1. | Cysteine desulfurase. | 0.707 |
| CSIRO_0234 | CSIRO_4093 | CSIRO_0234 | CSIRO_4093 | Molybdopterin converting factor subunit 1. | Hypothetical protein. | 0.686 |
| CSIRO_0234 | cysC | CSIRO_0234 | CSIRO_1510 | Molybdopterin converting factor subunit 1. | Sulfate adenylyltransferase subunit 1/ adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. | 0.781 |
| CSIRO_0234 | mnmA | CSIRO_0234 | CSIRO_1673 | Molybdopterin converting factor subunit 1. | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.592 |
| CSIRO_1448 | CSIRO_1512 | CSIRO_1448 | CSIRO_1512 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.639 |
| CSIRO_1448 | CSIRO_1941 | CSIRO_1448 | CSIRO_1941 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | SirA-like protein; Belongs to the sulfur carrier protein TusA family. | 0.713 |
| CSIRO_1448 | CSIRO_4093 | CSIRO_1448 | CSIRO_4093 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Hypothetical protein. | 0.698 |
| CSIRO_1448 | cysC | CSIRO_1448 | CSIRO_1510 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Sulfate adenylyltransferase subunit 1/ adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. | 0.582 |
| CSIRO_1448 | gcvP | CSIRO_1448 | CSIRO_3708 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.946 |
| CSIRO_1448 | mnmA | CSIRO_1448 | CSIRO_1673 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.401 |
| CSIRO_1512 | CSIRO_1448 | CSIRO_1512 | CSIRO_1448 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.639 |
| CSIRO_1512 | CSIRO_1941 | CSIRO_1512 | CSIRO_1941 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | SirA-like protein; Belongs to the sulfur carrier protein TusA family. | 0.848 |
| CSIRO_1512 | CSIRO_3158 | CSIRO_1512 | CSIRO_3158 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Cysteine desulfurase. | 0.491 |
| CSIRO_1512 | CSIRO_4093 | CSIRO_1512 | CSIRO_4093 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Hypothetical protein. | 0.482 |
| CSIRO_1512 | cysC | CSIRO_1512 | CSIRO_1510 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Sulfate adenylyltransferase subunit 1/ adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. | 0.986 |
| CSIRO_1941 | CSIRO_0234 | CSIRO_1941 | CSIRO_0234 | SirA-like protein; Belongs to the sulfur carrier protein TusA family. | Molybdopterin converting factor subunit 1. | 0.697 |
| CSIRO_1941 | CSIRO_1448 | CSIRO_1941 | CSIRO_1448 | SirA-like protein; Belongs to the sulfur carrier protein TusA family. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.713 |
| CSIRO_1941 | CSIRO_1512 | CSIRO_1941 | CSIRO_1512 | SirA-like protein; Belongs to the sulfur carrier protein TusA family. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.848 |