Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CSIRO_2147hydroxymethylglutaryl-CoA reductase; Belongs to the HMG-CoA reductase family. (427 aa)    
Predicted Functional Partners:
CSIRO_2146
Hypothetical protein.
       0.773
CSIRO_2145
Aspartate aminotransferase.
 
     0.738
CSIRO_3035
hydroxymethylglutaryl-CoA lyase.
    
 0.700
CSIRO_2148
ABC transporter substrate-binding protein.
       0.679
CSIRO_1765
Bifunctional; octaprenyl-diphosphate synthase/ dimethylallyltransferase/ geranyltranstransferase (farnesyldiphosphate synthase)/ geranylgeranyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family.
 
 
 0.553
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
 
  
 0.530
CSIRO_1107
Putative phosphotransferase.
    
  0.499
CSIRO_0691
Bifunctional; octaprenyl-diphosphate synthase/ dimethylallyltransferase/ geranyltranstransferase (farnesyldiphosphate synthase)/ geranylgeranyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family.
  
 
 0.487
CSIRO_2462
(R)-citramalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
    
 0.455
CSIRO_0396
Salicylate hydroxylase.
   
  
 0.428
Your Current Organism:
Bradyrhizobiaceae bacterium SG6C
NCBI taxonomy Id: 709797
Other names: B. bacterium SG-6C, Bradyrhizobiaceae bacterium SG-6C
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