| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CSIRO_1100 | CSIRO_1729 | CSIRO_1100 | CSIRO_1729 | Dihydrofolate synthase/ Folylpolyglutamate synthase; Bifunctional; Belongs to the folylpolyglutamate synthase family. | Anthranilate synthase. | 0.738 |
| CSIRO_1100 | CSIRO_2330 | CSIRO_1100 | CSIRO_2330 | Dihydrofolate synthase/ Folylpolyglutamate synthase; Bifunctional; Belongs to the folylpolyglutamate synthase family. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | 0.923 |
| CSIRO_1100 | CSIRO_2331 | CSIRO_1100 | CSIRO_2331 | Dihydrofolate synthase/ Folylpolyglutamate synthase; Bifunctional; Belongs to the folylpolyglutamate synthase family. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.854 |
| CSIRO_1100 | CSIRO_2332 | CSIRO_1100 | CSIRO_2332 | Dihydrofolate synthase/ Folylpolyglutamate synthase; Bifunctional; Belongs to the folylpolyglutamate synthase family. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.995 |
| CSIRO_1100 | CSIRO_3295 | CSIRO_1100 | CSIRO_3295 | Dihydrofolate synthase/ Folylpolyglutamate synthase; Bifunctional; Belongs to the folylpolyglutamate synthase family. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.855 |
| CSIRO_1100 | folE | CSIRO_1100 | CSIRO_3575 | Dihydrofolate synthase/ Folylpolyglutamate synthase; Bifunctional; Belongs to the folylpolyglutamate synthase family. | GTP cyclohydrolase Itype 1. | 0.692 |
| CSIRO_1100 | ispDF | CSIRO_1100 | CSIRO_2982 | Dihydrofolate synthase/ Folylpolyglutamate synthase; Bifunctional; Belongs to the folylpolyglutamate synthase family. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF); Belongs to the IspF family. In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily. | 0.544 |
| CSIRO_1729 | CSIRO_1100 | CSIRO_1729 | CSIRO_1100 | Anthranilate synthase. | Dihydrofolate synthase/ Folylpolyglutamate synthase; Bifunctional; Belongs to the folylpolyglutamate synthase family. | 0.738 |
| CSIRO_1729 | CSIRO_2330 | CSIRO_1729 | CSIRO_2330 | Anthranilate synthase. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | 0.930 |
| CSIRO_1729 | CSIRO_2331 | CSIRO_1729 | CSIRO_2331 | Anthranilate synthase. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.599 |
| CSIRO_1729 | CSIRO_2332 | CSIRO_1729 | CSIRO_2332 | Anthranilate synthase. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.962 |
| CSIRO_1729 | CSIRO_3295 | CSIRO_1729 | CSIRO_3295 | Anthranilate synthase. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.667 |
| CSIRO_1729 | folE | CSIRO_1729 | CSIRO_3575 | Anthranilate synthase. | GTP cyclohydrolase Itype 1. | 0.628 |
| CSIRO_1729 | ispDF | CSIRO_1729 | CSIRO_2982 | Anthranilate synthase. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF); Belongs to the IspF family. In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily. | 0.594 |
| CSIRO_1729 | queD | CSIRO_1729 | CSIRO_1719 | Anthranilate synthase. | Queuosine biosynthesis QueD. | 0.416 |
| CSIRO_2329 | CSIRO_2330 | CSIRO_2329 | CSIRO_2330 | methylmalonyl-CoA mutase. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | 0.620 |
| CSIRO_2329 | CSIRO_2331 | CSIRO_2329 | CSIRO_2331 | methylmalonyl-CoA mutase. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.559 |
| CSIRO_2329 | CSIRO_2332 | CSIRO_2329 | CSIRO_2332 | methylmalonyl-CoA mutase. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.567 |
| CSIRO_2329 | CSIRO_3947 | CSIRO_2329 | CSIRO_3947 | methylmalonyl-CoA mutase. | Fe-S protein. | 0.829 |
| CSIRO_2330 | CSIRO_1100 | CSIRO_2330 | CSIRO_1100 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | Dihydrofolate synthase/ Folylpolyglutamate synthase; Bifunctional; Belongs to the folylpolyglutamate synthase family. | 0.923 |