Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CSIRO_24412-hydroxy-3-oxopropionate reductase. (289 aa)    
Predicted Functional Partners:
CSIRO_1947
3-hydroxyisobutyrate dehydrogenase.
  
  
 
0.749
CSIRO_2539
3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.
  
  
 
0.746
CSIRO_2536
Methylmalonate-semialdehyde dehydrogenase.
 
 
 0.742
CSIRO_2538
3-hydroxyisobutyryl-CoA hydrolase.
 
 
 
  0.728
CSIRO_0368
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 
 0.700
CSIRO_2101
Aldehyde dehydrogenase.
  
 
 0.700
CSIRO_3411
Biotin carboxylase/ Biotin carboxyl carrier protein.
  
 
  0.700
CSIRO_4180
Glyoxylate carboligase; Belongs to the TPP enzyme family.
  
 
 0.693
CSIRO_2256
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Belongs to the HpcH/HpaI aldolase family.
  
 
 0.683
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
    
  0.678
Your Current Organism:
Bradyrhizobiaceae bacterium SG6C
NCBI taxonomy Id: 709797
Other names: B. bacterium SG-6C, Bradyrhizobiaceae bacterium SG-6C
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