| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CSIRO_1004 | CSIRO_2234 | CSIRO_1004 | CSIRO_2234 | Cytochrome P450 family protein. | Cytochrome P450. | 0.469 |
| CSIRO_1004 | CSIRO_2893 | CSIRO_1004 | CSIRO_2893 | Cytochrome P450 family protein. | Ubiquinone/menaquinone biosynthesis methyltransferase. | 0.512 |
| CSIRO_1004 | ubiE | CSIRO_1004 | CSIRO_1112 | Cytochrome P450 family protein. | Ubiquinone/menaquinone biosynthesis methyltransferase UbiE; Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family. | 0.512 |
| CSIRO_1448 | CSIRO_2234 | CSIRO_1448 | CSIRO_2234 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cytochrome P450. | 0.899 |
| CSIRO_1448 | CSIRO_2812 | CSIRO_1448 | CSIRO_2812 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.832 |
| CSIRO_1448 | CSIRO_2893 | CSIRO_1448 | CSIRO_2893 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Ubiquinone/menaquinone biosynthesis methyltransferase. | 0.522 |
| CSIRO_1448 | cysC | CSIRO_1448 | CSIRO_1510 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Sulfate adenylyltransferase subunit 1/ adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. | 0.508 |
| CSIRO_1448 | gcvP | CSIRO_1448 | CSIRO_3708 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.860 |
| CSIRO_1448 | ubiE | CSIRO_1448 | CSIRO_1112 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Ubiquinone/menaquinone biosynthesis methyltransferase UbiE; Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family. | 0.522 |
| CSIRO_2234 | CSIRO_1004 | CSIRO_2234 | CSIRO_1004 | Cytochrome P450. | Cytochrome P450 family protein. | 0.469 |
| CSIRO_2234 | CSIRO_1448 | CSIRO_2234 | CSIRO_1448 | Cytochrome P450. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.899 |
| CSIRO_2234 | CSIRO_2893 | CSIRO_2234 | CSIRO_2893 | Cytochrome P450. | Ubiquinone/menaquinone biosynthesis methyltransferase. | 0.522 |
| CSIRO_2234 | cysC | CSIRO_2234 | CSIRO_1510 | Cytochrome P450. | Sulfate adenylyltransferase subunit 1/ adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. | 0.970 |
| CSIRO_2234 | gcvP | CSIRO_2234 | CSIRO_3708 | Cytochrome P450. | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.456 |
| CSIRO_2234 | ubiE | CSIRO_2234 | CSIRO_1112 | Cytochrome P450. | Ubiquinone/menaquinone biosynthesis methyltransferase UbiE; Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family. | 0.522 |
| CSIRO_2812 | CSIRO_1448 | CSIRO_2812 | CSIRO_1448 | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.832 |
| CSIRO_2812 | CSIRO_2893 | CSIRO_2812 | CSIRO_2893 | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Ubiquinone/menaquinone biosynthesis methyltransferase. | 0.715 |
| CSIRO_2812 | cysC | CSIRO_2812 | CSIRO_1510 | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Sulfate adenylyltransferase subunit 1/ adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. | 0.416 |
| CSIRO_2812 | gcvP | CSIRO_2812 | CSIRO_3708 | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.914 |
| CSIRO_2812 | ubiE | CSIRO_2812 | CSIRO_1112 | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Ubiquinone/menaquinone biosynthesis methyltransferase UbiE; Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family. | 0.715 |