| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CSIRO_1448 | CSIRO_1450 | CSIRO_1448 | CSIRO_1450 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.994 |
| CSIRO_1448 | CSIRO_2211 | CSIRO_1448 | CSIRO_2211 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | O-acetylhomoserine sulfhydrylase/ O-succinylhomoserine sulfhydrylase; Bifunctional. | 0.855 |
| CSIRO_1448 | CSIRO_3221 | CSIRO_1448 | CSIRO_3221 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | enoyl-CoA hydratase. | 0.659 |
| CSIRO_1448 | CSIRO_3222 | CSIRO_1448 | CSIRO_3222 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | O-acetylhomoserine sulfhydrylase/ O-succinylhomoserine sulfhydrylase; Bifunctional. | 0.723 |
| CSIRO_1448 | CSIRO_3224 | CSIRO_1448 | CSIRO_3224 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | O-acetylhomoserine sulfhydrylase/ O-succinylhomoserine sulfhydrylase; Bifunctional. | 0.855 |
| CSIRO_1448 | CSIRO_3820 | CSIRO_1448 | CSIRO_3820 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Threonine dehydratase. | 0.846 |
| CSIRO_1448 | metXA | CSIRO_1448 | CSIRO_1594 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. | 0.898 |
| CSIRO_1448 | metZ | CSIRO_1448 | CSIRO_1266 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | O-acetylhomoserine sulfhydrylase/ O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.953 |
| CSIRO_1450 | CSIRO_1448 | CSIRO_1450 | CSIRO_1448 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.994 |
| CSIRO_1450 | CSIRO_2211 | CSIRO_1450 | CSIRO_2211 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | O-acetylhomoserine sulfhydrylase/ O-succinylhomoserine sulfhydrylase; Bifunctional. | 0.487 |
| CSIRO_1450 | CSIRO_3222 | CSIRO_1450 | CSIRO_3222 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | O-acetylhomoserine sulfhydrylase/ O-succinylhomoserine sulfhydrylase; Bifunctional. | 0.616 |
| CSIRO_1450 | CSIRO_3224 | CSIRO_1450 | CSIRO_3224 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | O-acetylhomoserine sulfhydrylase/ O-succinylhomoserine sulfhydrylase; Bifunctional. | 0.487 |
| CSIRO_1450 | CSIRO_3820 | CSIRO_1450 | CSIRO_3820 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | Threonine dehydratase. | 0.639 |
| CSIRO_1450 | metZ | CSIRO_1450 | CSIRO_1266 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | O-acetylhomoserine sulfhydrylase/ O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.891 |
| CSIRO_2211 | CSIRO_1448 | CSIRO_2211 | CSIRO_1448 | O-acetylhomoserine sulfhydrylase/ O-succinylhomoserine sulfhydrylase; Bifunctional. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.855 |
| CSIRO_2211 | CSIRO_1450 | CSIRO_2211 | CSIRO_1450 | O-acetylhomoserine sulfhydrylase/ O-succinylhomoserine sulfhydrylase; Bifunctional. | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.487 |
| CSIRO_2211 | CSIRO_3222 | CSIRO_2211 | CSIRO_3222 | O-acetylhomoserine sulfhydrylase/ O-succinylhomoserine sulfhydrylase; Bifunctional. | O-acetylhomoserine sulfhydrylase/ O-succinylhomoserine sulfhydrylase; Bifunctional. | 0.871 |
| CSIRO_2211 | metXA | CSIRO_2211 | CSIRO_1594 | O-acetylhomoserine sulfhydrylase/ O-succinylhomoserine sulfhydrylase; Bifunctional. | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. | 0.844 |
| CSIRO_2211 | metZ | CSIRO_2211 | CSIRO_1266 | O-acetylhomoserine sulfhydrylase/ O-succinylhomoserine sulfhydrylase; Bifunctional. | O-acetylhomoserine sulfhydrylase/ O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.516 |
| CSIRO_3221 | CSIRO_1448 | CSIRO_3221 | CSIRO_1448 | enoyl-CoA hydratase. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.659 |