| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CSIRO_0258 | CSIRO_1808 | CSIRO_0258 | CSIRO_1808 | Riboflavin kinase/ FMN adenylyltransferase; Bifunctional; Belongs to the ribF family. | 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.897 |
| CSIRO_0258 | CSIRO_2020 | CSIRO_0258 | CSIRO_2020 | Riboflavin kinase/ FMN adenylyltransferase; Bifunctional; Belongs to the ribF family. | Nitrilotriacetate monooxygenase component B. | 0.732 |
| CSIRO_0258 | CSIRO_3294 | CSIRO_0258 | CSIRO_3294 | Riboflavin kinase/ FMN adenylyltransferase; Bifunctional; Belongs to the ribF family. | Riboflavin synthase alpha chain. | 0.896 |
| CSIRO_0258 | CSIRO_3295 | CSIRO_0258 | CSIRO_3295 | Riboflavin kinase/ FMN adenylyltransferase; Bifunctional; Belongs to the ribF family. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.862 |
| CSIRO_0258 | ribH | CSIRO_0258 | CSIRO_3292 | Riboflavin kinase/ FMN adenylyltransferase; Bifunctional; Belongs to the ribF family. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.851 |
| CSIRO_1808 | CSIRO_0258 | CSIRO_1808 | CSIRO_0258 | 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | Riboflavin kinase/ FMN adenylyltransferase; Bifunctional; Belongs to the ribF family. | 0.897 |
| CSIRO_1808 | CSIRO_2020 | CSIRO_1808 | CSIRO_2020 | 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | Nitrilotriacetate monooxygenase component B. | 0.440 |
| CSIRO_1808 | CSIRO_2332 | CSIRO_1808 | CSIRO_2332 | 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.655 |
| CSIRO_1808 | CSIRO_3294 | CSIRO_1808 | CSIRO_3294 | 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | Riboflavin synthase alpha chain. | 0.999 |
| CSIRO_1808 | CSIRO_3295 | CSIRO_1808 | CSIRO_3295 | 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.999 |
| CSIRO_1808 | glyA | CSIRO_1808 | CSIRO_3297 | 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.660 |
| CSIRO_1808 | nrdR | CSIRO_1808 | CSIRO_3296 | 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | Ribonucleotide reductase transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.677 |
| CSIRO_1808 | nusB | CSIRO_1808 | CSIRO_3291 | 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | Transcription termination protein NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.770 |
| CSIRO_1808 | ribH | CSIRO_1808 | CSIRO_3292 | 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.999 |
| CSIRO_2020 | CSIRO_0258 | CSIRO_2020 | CSIRO_0258 | Nitrilotriacetate monooxygenase component B. | Riboflavin kinase/ FMN adenylyltransferase; Bifunctional; Belongs to the ribF family. | 0.732 |
| CSIRO_2020 | CSIRO_1808 | CSIRO_2020 | CSIRO_1808 | Nitrilotriacetate monooxygenase component B. | 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.440 |
| CSIRO_2020 | CSIRO_3294 | CSIRO_2020 | CSIRO_3294 | Nitrilotriacetate monooxygenase component B. | Riboflavin synthase alpha chain. | 0.593 |
| CSIRO_2332 | CSIRO_1808 | CSIRO_2332 | CSIRO_1808 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.655 |
| CSIRO_2332 | CSIRO_3294 | CSIRO_2332 | CSIRO_3294 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Riboflavin synthase alpha chain. | 0.571 |
| CSIRO_2332 | CSIRO_3295 | CSIRO_2332 | CSIRO_3295 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.724 |