| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CSIRO_0258 | CSIRO_1100 | CSIRO_0258 | CSIRO_1100 | Riboflavin kinase/ FMN adenylyltransferase; Bifunctional; Belongs to the ribF family. | Dihydrofolate synthase/ Folylpolyglutamate synthase; Bifunctional; Belongs to the folylpolyglutamate synthase family. | 0.596 |
| CSIRO_0258 | CSIRO_1808 | CSIRO_0258 | CSIRO_1808 | Riboflavin kinase/ FMN adenylyltransferase; Bifunctional; Belongs to the ribF family. | 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.873 |
| CSIRO_0258 | CSIRO_3294 | CSIRO_0258 | CSIRO_3294 | Riboflavin kinase/ FMN adenylyltransferase; Bifunctional; Belongs to the ribF family. | Riboflavin synthase alpha chain. | 0.774 |
| CSIRO_0258 | CSIRO_3295 | CSIRO_0258 | CSIRO_3295 | Riboflavin kinase/ FMN adenylyltransferase; Bifunctional; Belongs to the ribF family. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.914 |
| CSIRO_0258 | ribH | CSIRO_0258 | CSIRO_3292 | Riboflavin kinase/ FMN adenylyltransferase; Bifunctional; Belongs to the ribF family. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.962 |
| CSIRO_1100 | CSIRO_0258 | CSIRO_1100 | CSIRO_0258 | Dihydrofolate synthase/ Folylpolyglutamate synthase; Bifunctional; Belongs to the folylpolyglutamate synthase family. | Riboflavin kinase/ FMN adenylyltransferase; Bifunctional; Belongs to the ribF family. | 0.596 |
| CSIRO_1100 | CSIRO_1808 | CSIRO_1100 | CSIRO_1808 | Dihydrofolate synthase/ Folylpolyglutamate synthase; Bifunctional; Belongs to the folylpolyglutamate synthase family. | 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.823 |
| CSIRO_1100 | CSIRO_2664 | CSIRO_1100 | CSIRO_2664 | Dihydrofolate synthase/ Folylpolyglutamate synthase; Bifunctional; Belongs to the folylpolyglutamate synthase family. | Hypothetical protein. | 0.647 |
| CSIRO_1100 | CSIRO_3295 | CSIRO_1100 | CSIRO_3295 | Dihydrofolate synthase/ Folylpolyglutamate synthase; Bifunctional; Belongs to the folylpolyglutamate synthase family. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.852 |
| CSIRO_1100 | CSIRO_4025 | CSIRO_1100 | CSIRO_4025 | Dihydrofolate synthase/ Folylpolyglutamate synthase; Bifunctional; Belongs to the folylpolyglutamate synthase family. | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.717 |
| CSIRO_1100 | folE | CSIRO_1100 | CSIRO_3575 | Dihydrofolate synthase/ Folylpolyglutamate synthase; Bifunctional; Belongs to the folylpolyglutamate synthase family. | GTP cyclohydrolase Itype 1. | 0.633 |
| CSIRO_1808 | CSIRO_0258 | CSIRO_1808 | CSIRO_0258 | 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | Riboflavin kinase/ FMN adenylyltransferase; Bifunctional; Belongs to the ribF family. | 0.873 |
| CSIRO_1808 | CSIRO_1100 | CSIRO_1808 | CSIRO_1100 | 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | Dihydrofolate synthase/ Folylpolyglutamate synthase; Bifunctional; Belongs to the folylpolyglutamate synthase family. | 0.823 |
| CSIRO_1808 | CSIRO_3294 | CSIRO_1808 | CSIRO_3294 | 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | Riboflavin synthase alpha chain. | 0.999 |
| CSIRO_1808 | CSIRO_3295 | CSIRO_1808 | CSIRO_3295 | 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.999 |
| CSIRO_1808 | folE | CSIRO_1808 | CSIRO_3575 | 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | GTP cyclohydrolase Itype 1. | 0.823 |
| CSIRO_1808 | moaA | CSIRO_1808 | CSIRO_2447 | 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | Molybdenum cofactor biosynthesis protein MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.674 |
| CSIRO_1808 | ribH | CSIRO_1808 | CSIRO_3292 | 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.997 |
| CSIRO_2664 | CSIRO_1100 | CSIRO_2664 | CSIRO_1100 | Hypothetical protein. | Dihydrofolate synthase/ Folylpolyglutamate synthase; Bifunctional; Belongs to the folylpolyglutamate synthase family. | 0.647 |
| CSIRO_2664 | CSIRO_3295 | CSIRO_2664 | CSIRO_3295 | Hypothetical protein. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.835 |