| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CSIRO_3614 | CSIRO_3615 | CSIRO_3614 | CSIRO_3615 | Phenylacetic acid degradation-related protein. | Molybdopterin binding motif-containing protein. | 0.783 |
| CSIRO_3614 | gpt | CSIRO_3614 | CSIRO_3613 | Phenylacetic acid degradation-related protein. | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.771 |
| CSIRO_3615 | CSIRO_3614 | CSIRO_3615 | CSIRO_3614 | Molybdopterin binding motif-containing protein. | Phenylacetic acid degradation-related protein. | 0.783 |
| CSIRO_3615 | gpt | CSIRO_3615 | CSIRO_3613 | Molybdopterin binding motif-containing protein. | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.785 |
| CSIRO_3615 | soxB | CSIRO_3615 | CSIRO_2118 | Molybdopterin binding motif-containing protein. | Sulfur oxidation protein SoxB; Belongs to the 5'-nucleotidase family. | 0.642 |
| apt | gmk | CSIRO_1730 | CSIRO_2621 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.888 |
| apt | gpt | CSIRO_1730 | CSIRO_3613 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.709 |
| apt | guaA | CSIRO_1730 | CSIRO_2557 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.978 |
| apt | guaB | CSIRO_1730 | CSIRO_2551 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.820 |
| apt | purA | CSIRO_1730 | CSIRO_0151 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.581 |
| apt | purH | CSIRO_1730 | CSIRO_0983 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | IMP cyclohydrolase/ phosphoribosylaminoimidazolecarboxamide formyltransferase; Bifunctional. | 0.862 |
| apt | rdgB | CSIRO_1730 | CSIRO_0896 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Nucleoside 5-triphosphatase RdgB; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.682 |
| apt | soxB | CSIRO_1730 | CSIRO_2118 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Sulfur oxidation protein SoxB; Belongs to the 5'-nucleotidase family. | 0.703 |
| gmk | apt | CSIRO_2621 | CSIRO_1730 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.888 |
| gmk | gpt | CSIRO_2621 | CSIRO_3613 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.686 |
| gmk | guaA | CSIRO_2621 | CSIRO_2557 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.907 |
| gmk | guaB | CSIRO_2621 | CSIRO_2551 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.823 |
| gmk | rdgB | CSIRO_2621 | CSIRO_0896 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Nucleoside 5-triphosphatase RdgB; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.517 |
| gmk | soxB | CSIRO_2621 | CSIRO_2118 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Sulfur oxidation protein SoxB; Belongs to the 5'-nucleotidase family. | 0.620 |
| gpt | CSIRO_3614 | CSIRO_3613 | CSIRO_3614 | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | Phenylacetic acid degradation-related protein. | 0.771 |